| Literature DB >> 2551309 |
N Miyasaka1, K Yamaoka, M Tateishi, K Nishioka, K Yamamoto.
Abstract
The following results suggest that EBV might be involved in the mechanism of polyclonal B-cell activation of Sjögren's syndrome (SS). (1) The levels of serum anti-VCA antibodies of both IgG and IgM class were significantly elevated in SS. (2) Excretion of EBV from the oropharynx was frequently observed in SS. (3) Spontaneously transformed B-cell lines producing a large amount of transforming EBV were established preferentially from SS. (4) An EBV-specific regulatory mechanism was impaired in SS.Entities:
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Year: 1989 PMID： 2551309 DOI： 10.1016/0896-8411(89)90171-6
Source DB: PubMed Journal: J Autoimmun ISSN： 0896-8411 Impact factor: 7.094