Literature DB >> 25512473

Facilitators and barriers to adherence in the initiation phase of Disease-modifying Antirheumatic Drug (DMARD) use in patients with arthritis who recently started their first DMARD treatment.

Annelieke Pasma1, Adriaan van 't Spijker2, Jolanda J Luime2, Margot J M Walter2, Jan J V Busschbach2, Johanna M W Hazes2.   

Abstract

OBJECTIVE: To explore themes associated with adherence in the initiation phase for first-time use of disease-modifying antirheumatic drugs (DMARD) in patients with inflammatory arthritis using focus groups and individual interviews.
METHODS: Thirty-three patients were interviewed in focus groups and individual interviews. Interviews were transcribed verbatim and imported into ATLAS.ti software (Scientific Software Development GmbH). Responses that included reasons for adherence or nonadherence in the initiation phase were extracted and coded by 2 coders separately. The 2 coders conferred until consensus on the codes was achieved. Codes were classified into overarching themes.
RESULTS: Five themes emerged: (1) symptom severity, (2) experiences with medication, (3) perceptions about medication and the illness, (4) information about medication, and (5) communication style and trust in the rheumatologist.
CONCLUSION: Perceptions about medication and the communication style with, and trust in, the rheumatologist were mentioned the most in relation to starting DMARD. The rheumatologist plays a crucial role in influencing adherence behavior by addressing perceptions about medication, providing information, and establishing trust in the treatment plan.

Entities:  

Keywords:  DISEASE-MODIFYING ANTIRHEUMATIC DRUGS; MEDICATION ADHERENCE; PSORIATIC ARTHRITIS; QUALITATIVE RESEARCH; RHEUMATOID ARTHRITIS

Mesh:

Substances:

Year:  2014        PMID: 25512473     DOI: 10.3899/jrheum.140693

Source DB:  PubMed          Journal:  J Rheumatol        ISSN: 0315-162X            Impact factor:   4.666


  10 in total

1.  Qualitative assessment of medication adherence in patients with rheumatic diseases on biologic therapy.

Authors:  Sudha Raghunath; Raif Hijjawi; Elizabeth Hoon; E Michael Shanahan; Fiona Goldblatt
Journal:  Clin Rheumatol       Date:  2019-06-06       Impact factor: 2.980

2.  Patient Perspectives on DMARD Safety Concerns in Rheumatology Trials: Results from Inflammatory Arthritis Patient Focus Groups and OMERACT Attendees Discussion.

Authors:  Kathleen M Andersen; Ayano Kelly; Anne Lyddiatt; Clifton O Bingham; Vivian P Bykerk; Adena Batterman; Joan Westreich; Michelle K Jones; Marita Cross; Peter M Brooks; Lyn March; Beverley Shea; Peter Tugwell; Lee S Simon; Robin Christensen; Susan J Bartlett
Journal:  J Rheumatol       Date:  2019-02-15       Impact factor: 4.666

3.  Rheumatoid Arthritis Patients' Motivations for Accepting or Resisting Disease-Modifying Antirheumatic Drug Treatment Regimens.

Authors:  Yomei Shaw; Ilinca D Metes; Kaleb Michaud; Julie M Donohue; Mark S Roberts; Marc C Levesque; Judy C Chang
Journal:  Arthritis Care Res (Hoboken)       Date:  2018-03-11       Impact factor: 4.794

4.  Does non-adherence to DMARDs influence hospital-related healthcare costs for early arthritis in the first year of treatment?

Authors:  Annelieke Pasma; Charlotte Schenk; Reinier Timman; Adriaan van 't Spijker; Cathelijne Appels; Willemijn H van der Laan; Bart van den Bemt; Robert Goekoop; Johanna M W Hazes; Jan J V Busschbach
Journal:  PLoS One       Date:  2017-02-02       Impact factor: 3.240

5.  Patients' Attitudes and Experiences of Disease-Modifying Antirheumatic Drugs in Rheumatoid Arthritis and Spondyloarthritis: A Qualitative Synthesis.

Authors:  Ayano Kelly; Kathleen Tymms; David J Tunnicliffe; Daniel Sumpton; Chandima Perera; Kieran Fallon; Jonathan C Craig; Walter Abhayaratna; Allison Tong
Journal:  Arthritis Care Res (Hoboken)       Date:  2018-03-24       Impact factor: 4.794

6.  Use of rheumatology-specific patient navigators to understand and reduce barriers to medication adherence: Analysis of qualitative findings.

Authors:  Alyssa Wohlfahrt; Anarosa Campos; Maura D Iversen; Joshua J Gagne; Elena Massarotti; Daniel H Solomon; Candace H Feldman
Journal:  PLoS One       Date:  2018-07-19       Impact factor: 3.240

7.  Real-world questions and concerns about disease-modifying antirheumatic drugs (DMARDs): a retrospective analysis of questions to a medicine call center.

Authors:  Hiba El Masri; Samantha A Hollingworth; Mieke van Driel; Helen Benham; Treasure M McGuire
Journal:  BMC Rheumatol       Date:  2020-06-16

8.  A Serious Puzzle Game to Enhance Adherence to Antirheumatic Drugs in Patients With Rheumatoid Arthritis: Systematic Development Using Intervention Mapping.

Authors:  Bart Ph Pouls; Charlotte L Bekker; Sandra van Dulmen; Johanna E Vriezekolk; Bart Jf van den Bemt
Journal:  JMIR Serious Games       Date:  2022-02-18       Impact factor: 3.364

9.  Non-adherence to disease-modifying antirheumatic drugs is associated with higher disease activity in early arthritis patients in the first year of the disease.

Authors:  Annelieke Pasma; Charlotte V Schenk; Reinier Timman; Jan J V Busschbach; Bart J F van den Bemt; Esmeralda Molenaar; Willemijn H van der Laan; Saskia Schrauwen; Adriaan Van't Spijker; Johanna M W Hazes
Journal:  Arthritis Res Ther       Date:  2015-10-08       Impact factor: 5.156

10.  I do not want to suppress the natural process of inflammation: new insights on factors associated with non-adherence in rheumatoid arthritis.

Authors:  Valentin Ritschl; Angelika Lackner; Carina Boström; Erika Mosor; Michaela Lehner; Maisa Omara; Romualdo Ramos; Paul Studenic; Josef Sebastian Smolen; Tanja Alexandra Stamm
Journal:  Arthritis Res Ther       Date:  2018-10-19       Impact factor: 5.156

  10 in total

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