Literature DB >> 25512426

Synergistic activity of chloroquine with fluconazole against fluconazole-resistant isolates of Candida species.

Yali Li1, Zhe Wan1, Wei Liu2, Ruoyu Li1.   

Abstract

The in vitro activity of chloroquine and the interactions of chloroquine combined with fluconazole against 37 Candida isolates were tested using the broth microdilution, disk diffusion, and Etest susceptibility tests. Synergistic effect was detected with 6 of 9 fluconazole-resistant Candida albicans isolates, with Candida krusei ATCC 6258, and with all 12 fluconazole-resistant Candida tropicalis isolates.
Copyright © 2015, American Society for Microbiology. All Rights Reserved.

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Year:  2014        PMID： 25512426      PMCID： PMC4335839          DOI： 10.1128/AAC.04417-14

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  37 in total

1.  In vitro antifungal susceptibility of filamentous fungi causing rare infections: synergy testing of amphotericin B, posaconazole and anidulafungin in pairs.

Authors:  Maria Drogari-Apiranthitou; Foteini-Despina Mantopoulou; Anna Skiada; Lambrini Kanioura; Maria Grammatikou; Georgia Vrioni; Aggeliki Mitroussia-Ziouva; Athanassios Tsakris; George Petrikkos
Journal:  J Antimicrob Chemother       Date:  2012-04-25       Impact factor: 5.790

2.  An in vitro repositioning study reveals antifungal potential of chloroquine to inhibit growth and morphogenesis in Candida albicans.

Authors:  Ravikumar B Shinde; Sandeep B Rajput; Jayant S Raut; S Mohan Karuppayil
Journal:  J Gen Appl Microbiol       Date:  2013       Impact factor: 1.452

3.  Pharmacokinetics, pharmacodynamics, and allometric scaling of chloroquine in a murine malaria model.

Authors:  Brioni R Moore; Madhu Page-Sharp; Jillian R Stoney; Kenneth F Ilett; Jeffrey D Jago; Kevin T Batty
Journal:  Antimicrob Agents Chemother       Date:  2011-06-06       Impact factor: 5.191

4.  Invasive candidiasis in intensive care units in China: a multicentre prospective observational study.

Authors:  Fengmei Guo; Yi Yang; Yan Kang; Bin Zang; Wei Cui; Bingyu Qin; Yingzhi Qin; Qiang Fang; Tiehe Qin; Dongpo Jiang; Weiqin Li; Qin Gu; Hongsheng Zhao; Dawei Liu; Xiangdong Guan; Jianguo Li; Xiaochun Ma; Kaijiang Yu; Dechang Chan; Jing Yan; Yaoqing Tang; Wei Liu; Ruoyu Li; Haibo Qiu
Journal:  J Antimicrob Chemother       Date:  2013-03-29       Impact factor: 5.790

5.  Antifungal activity of geldanamycin alone or in combination with fluconazole against Candida species.

Authors:  Jinqing Zhang; Wei Liu; Jingwen Tan; Yi Sun; Zhe Wan; Ruoyu Li
Journal:  Mycopathologia       Date:  2013-01-23       Impact factor: 2.574

6.  Model system to define pharmacokinetic requirements for antimalarial drug efficacy.

Authors:  Rahul P Bakshi; Elizabeth Nenortas; Abhai K Tripathi; David J Sullivan; Theresa A Shapiro
Journal:  Sci Transl Med       Date:  2013-10-02       Impact factor: 17.956

7.  Epidemiology, species distribution, antifungal susceptibility and outcome of nosocomial candidemia in a tertiary care hospital in Italy.

Authors:  Matteo Bassetti; Lucia Taramasso; Elena Nicco; Maria Pia Molinari; Michele Mussap; Claudio Viscoli
Journal:  PLoS One       Date:  2011-09-15       Impact factor: 3.240

8.  Pharmacokinetic interactions between primaquine and chloroquine.

Authors:  Sasithon Pukrittayakamee; Joel Tarning; Podjanee Jittamala; Prakaykaew Charunwatthana; Saranath Lawpoolsri; Sue J Lee; Warunee Hanpithakpong; Borimas Hanboonkunupakarn; Nicholas P J Day; Elizabeth A Ashley; Nicholas J White
Journal:  Antimicrob Agents Chemother       Date:  2014-03-31       Impact factor: 5.191

9.  Cell wall perturbation sensitizes fungi to the antimalarial drug chloroquine.

Authors:  Farida Islahudin; Combiz Khozoie; Steven Bates; Kang-Nee Ting; Richard J Pleass; Simon V Avery
Journal:  Antimicrob Agents Chemother       Date:  2013-06-03       Impact factor: 5.191

10.  Chloroquine sensitizes biofilms of Candida albicans to antifungal azoles.

Authors:  Ravikumar Bapurao Shinde; Jayant Shankar Raut; Nitin Mahendra Chauhan; Sankunny Mohan Karuppayil
Journal:  Braz J Infect Dis       Date:  2013-04-18       Impact factor: 3.257
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  6 in total

1.  diskImageR: quantification of resistance and tolerance to antimicrobial drugs using disk diffusion assays.

Authors:  Aleeza C Gerstein; Alexander Rosenberg; Inbal Hecht; Judith Berman
Journal:  Microbiology       Date:  2016-04-27       Impact factor: 2.777

Review 2.  Antifungal Susceptibly Testing by Concentration Gradient Strip Etest Method for Fungal Isolates: A Review.

Authors:  Eric Dannaoui; Ana Espinel-Ingroff
Journal:  J Fungi (Basel)       Date:  2019-11-22

3.  Coadministration of Ginger Extract and Fluconazole Shows a Synergistic Effect in the Treatment of Drug-Resistant Vulvovaginal Candidiasis.

Authors:  Arif Khan; Mohd Azam; Masood Alam Khan; Khaled S Allemailem; Faris Alrumaihi; Ahmad Almatroudi; Fahad A Alhumaydhi; Hafiz Iqtidar Ahmad; Masih Uzzaman Khan
Journal:  Infect Drug Resist       Date:  2021-04-21       Impact factor: 4.003

Review 4.  Techniques for the Assessment of In Vitro and In Vivo Antifungal Combinations.

Authors:  Anne-Laure Bidaud; Patrick Schwarz; Guillaume Herbreteau; Eric Dannaoui
Journal:  J Fungi (Basel)       Date:  2021-02-04

Review 5.  Augmenting Azoles with Drug Synergy to Expand the Antifungal Toolbox.

Authors:  Aidan Kane; Dee A Carter
Journal:  Pharmaceuticals (Basel)       Date:  2022-04-14

6.  Hydroxychloroquine may reduce risk of Pneumocystis pneumonia in lupus patients: a Nationwide, population-based case-control study.

Authors:  Kai-Jieh Yeo; Hsin-Hua Chen; Yi-Ming Chen; Ching-Heng Lin; Der-Yuan Chen; Chih-Ming Lai; Wen-Cheng Chao
Journal:  BMC Infect Dis       Date:  2020-02-10       Impact factor: 3.090
  6 in total

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