Mohammed F Faramawi1, Lori Fischbach2, Robert Delongchamp2, Victor Cardenas2, Saly Abouelenien3, Irene P Chedjieu2, Noha Taha4. 1. Department of Epidemiology, College of Public Health, University of Arkansas for Medical Sciences, Little Rock, AR 77205, USA Department of Public Health, National Liver Institute, Menofiya University, Shebin El koum, Menofiya, Egypt. 2. Department of Epidemiology, College of Public Health, University of Arkansas for Medical Sciences, Little Rock, AR 77205, USA. 3. Clinical Translational Institute, University of Arkansas for Medical Sciences, Little Rock, AR, USA. 4. Department of Internal Medicine, Faculty of Medicine, Kasr Al-Eini Hospital, Cairo University, Giza, Egypt.
Abstract
BACKGROUND: Evidence has accumulated showing that blood pressure variability is associated with cardiovascular disease. A substantial increase in the prevalence of obesity has been documented globally. Our objective was to examine the relation of total and central obesity on visit-to-visit blood pressure variability. METHODS: We used data collected from the cross-sectional Third National Health and Nutrition Examination Survey, to examine the association of visit-to-visit blood pressure variability with body mass index and waist circumference. RESULTS: The analysis included 14,988 participants. The participants' mean age was 43.45 years. Visit-to-visit systolic blood pressure variability was associated with a body mass index ≥30 and a large waist circumference (beta coefficients were 0.25 and 0.31, respectively, P-values < 0.01). Neither the bivariate nor the multivariable analyses showed significant relationships between the obesity indicators and diastolic blood pressure variability. CONCLUSIONS: Obesity is associated with visit-to-visit systolic blood pressure variability. Additional research is required to replicate the reported results in prospective studies and evaluate approaches to reduce blood pressure variability observed in clinical settings among obese persons to reduce its subsequent complications.
BACKGROUND: Evidence has accumulated showing that blood pressure variability is associated with cardiovascular disease. A substantial increase in the prevalence of obesity has been documented globally. Our objective was to examine the relation of total and central obesity on visit-to-visit blood pressure variability. METHODS: We used data collected from the cross-sectional Third National Health and Nutrition Examination Survey, to examine the association of visit-to-visit blood pressure variability with body mass index and waist circumference. RESULTS: The analysis included 14,988 participants. The participants' mean age was 43.45 years. Visit-to-visit systolic blood pressure variability was associated with a body mass index ≥30 and a large waist circumference (beta coefficients were 0.25 and 0.31, respectively, P-values < 0.01). Neither the bivariate nor the multivariable analyses showed significant relationships between the obesity indicators and diastolic blood pressure variability. CONCLUSIONS:Obesity is associated with visit-to-visit systolic blood pressure variability. Additional research is required to replicate the reported results in prospective studies and evaluate approaches to reduce blood pressure variability observed in clinical settings among obesepersons to reduce its subsequent complications.
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