Xin Li1, Qiang Zhang2, Changsong Zhao1, Sheng Sun1, Juan Cai1. 1. Department of Orthopedics, Beijing Ditan Hospital, Capital Medical University, Beijing 100015, China. 2. Department of Orthopedics, Beijing Ditan Hospital, Capital Medical University, Beijing 100015, China. Email: zhangqwte@sina.com.
Abstract
OBJECTIVE: To observe the healing status of surgical incisions in human immunodeficiency virus (HIV)-positive patients with fractures and explore the factors related with poor wound healing, treatment and preventive measures. METHODS: Retrospective analyses were performed for the clinical data of 61 HIV-positive patients with fractures. And the influencing factors, treatment and outcomes of poor wound healing were analyzed. RESULTS: Among them, the healing status was good (n = 50) and poor (n = 11). And the outcomes included redness (n = 10), oozing (n = 8), split (n = 3), infection (n = 2), hematoma (n = 1), fat liquefaction (n = 2) and delayed healing (n = 2). All healed well after treatment. There was no infection or death during the follow-up period. Compared with HIV-negative patients, it was not statistically significant in wound infection. However, poor healing rates were significantly different (P < 0.05). The risk factors included advanced age, low body mass index, low albumin, low hemoglobin, low total lymphocyte count, low CD4⁺ T lymphocyte count, high HIV infection clinical stage, long operative duration, emergency surgery and incision contamination. CONCLUSION: In HIV-positive patients with fractures, the healing of surgical incision is generally good. However few have poor wound healing due to multiple factors. If poor healing is identified early and handled timely and correctly, good healing ensues.
OBJECTIVE: To observe the healing status of surgical incisions in human immunodeficiency virus (HIV)-positivepatients with fractures and explore the factors related with poor wound healing, treatment and preventive measures. METHODS: Retrospective analyses were performed for the clinical data of 61 HIV-positivepatients with fractures. And the influencing factors, treatment and outcomes of poor wound healing were analyzed. RESULTS: Among them, the healing status was good (n = 50) and poor (n = 11). And the outcomes included redness (n = 10), oozing (n = 8), split (n = 3), infection (n = 2), hematoma (n = 1), fat liquefaction (n = 2) and delayed healing (n = 2). All healed well after treatment. There was no infection or death during the follow-up period. Compared with HIV-negative patients, it was not statistically significant in wound infection. However, poor healing rates were significantly different (P < 0.05). The risk factors included advanced age, low body mass index, low albumin, low hemoglobin, low total lymphocyte count, low CD4⁺ T lymphocyte count, high HIV infection clinical stage, long operative duration, emergency surgery and incision contamination. CONCLUSION: In HIV-positivepatients with fractures, the healing of surgical incision is generally good. However few have poor wound healing due to multiple factors. If poor healing is identified early and handled timely and correctly, good healing ensues.