Misty A W Hawkins1, Julie T Schaefer2, John Gunstad2, Mary A Dolansky3, Joseph D Redle4, Richard Josephson5, Shirley M Moore3, Joel W Hughes6. 1. Department of Psychology, Kent State University, Kent, OH. Electronic address: mhawki15@kent.edu. 2. Department of Psychology, Kent State University, Kent, OH. 3. Frances Payne Bolton School of Nursing, Case Western Reserve University, Cleveland, OH. 4. Cardiovascular Research Institute, Summa Health System, Akron City Hospital, Akron, OH. 5. School of Medicine, Case Western Reserve University, Cleveland, OH; Harrington Heart & Vascular Institute, University Hospitals, Cleveland, OH. 6. Department of Psychology, Kent State University, Kent, OH; Cardiovascular Research Institute, Summa Health System, Akron City Hospital, Akron, OH.
Abstract
PURPOSE: The aim of this study was to determine whether patients with heart failure (HF) have distinct profiles of cognitive impairment. BACKGROUND: Cognitive impairment is common in HF. Recent work found three cognitive profiles in HF patients-(1) intact, (2) impaired, and (3) memory-impaired. We examined the reproducibility of these profiles and clarified mechanisms. METHODS: HF patients (68.6 ± 9.7 years; N=329) completed neuropsychological testing. Composite scores were created for cognitive domains and used to identify clusters via agglomerative-hierarchical cluster analysis. RESULTS: A 3-cluster solution emerged. Cluster 1 (n=109) had intact cognition. Cluster 2 (n=123) was impaired across all domains. Cluster 3 (n=97) had impaired memory only. Clusters differed in age, race, education, SES, IQ, BMI, and diabetes (ps ≤ .026) but not in mood, anxiety, cardiovascular, or pulmonary disease (ps ≥ .118). CONCLUSIONS: We replicated three distinct patterns of cognitive function in persons with HF. These profiles may help providers offer tailored care to patients with different cognitive and clinical needs.
PURPOSE: The aim of this study was to determine whether patients with heart failure (HF) have distinct profiles of cognitive impairment. BACKGROUND:Cognitive impairment is common in HF. Recent work found three cognitive profiles in HF patients-(1) intact, (2) impaired, and (3) memory-impaired. We examined the reproducibility of these profiles and clarified mechanisms. METHODS: HF patients (68.6 ± 9.7 years; N=329) completed neuropsychological testing. Composite scores were created for cognitive domains and used to identify clusters via agglomerative-hierarchical cluster analysis. RESULTS: A 3-cluster solution emerged. Cluster 1 (n=109) had intact cognition. Cluster 2 (n=123) was impaired across all domains. Cluster 3 (n=97) had impaired memory only. Clusters differed in age, race, education, SES, IQ, BMI, and diabetes (ps ≤ .026) but not in mood, anxiety, cardiovascular, or pulmonary disease (ps ≥ .118). CONCLUSIONS: We replicated three distinct patterns of cognitive function in persons with HF. These profiles may help providers offer tailored care to patients with different cognitive and clinical needs.
Authors: Raymond L C Vogels; Joukje M Oosterman; Barbera van Harten; Philip Scheltens; Wiesje M van der Flier; Jutta M Schroeder-Tanka; Henry C Weinstein Journal: J Am Geriatr Soc Date: 2007-08-28 Impact factor: 5.562
Authors: Debra K Moser; Cynthia Arslanian-Engoren; Martha J Biddle; Misook Lee Chung; Rebecca L Dekker; Muna H Hammash; Gia Mudd-Martin; Abdullah S Alhurani; Terry A Lennie Journal: Curr Cardiol Rep Date: 2016-12 Impact factor: 2.931
Authors: Eliezer L Bose; Gilles Clermont; Lujie Chen; Artur W Dubrawski; Dianxu Ren; Leslie A Hoffman; Michael R Pinsky; Marilyn Hravnak Journal: J Clin Monit Comput Date: 2017-02-22 Impact factor: 2.502
Authors: Emily C Gathright; Mary A Dolansky; John Gunstad; Richard A Josephson; Shirley M Moore; Joel W Hughes Journal: Eur J Cardiovasc Nurs Date: 2019-07-25 Impact factor: 3.908
Authors: Victoria Sanborn; John Gunstad; Roman Shrestha; Colleen B Mistler; Michael M Copenhaver Journal: Appl Neuropsychol Adult Date: 2020-05-28 Impact factor: 2.050