Literature DB >> 2550978

The EcoDXX1 restriction and modification system: cloning the genes and homology to type I restriction and modification systems.

E Skrzypek1, A Piekarowicz.   

Abstract

The Escherichia coli plasmid pDXX1 codes for a type I restriction and modification system, EcoDXX1. A 15.5-kb BamHI fragment from pDXX1 has been cloned and contains the hsdR, hsdM, and hsdS genes that encode the EcoDXX1 system. The EcoDXX1 hsd genes can complement the gene products of the EcoR124 and EcoR124/3 hsd systems, but not those of EcoK and EcoB. Hybridization experiments using EcoDXX1 hsd genes as a probe demonstrate homology between EcoDXX1 and EcoR124 and EcoR124/3 restriction-modification systems, but weak or no homology between EcoDXX1 and EcoK or EcoB systems.

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Year:  1989        PMID: 2550978     DOI: 10.1016/0147-619x(89)90043-7

Source DB:  PubMed          Journal:  Plasmid        ISSN: 0147-619X            Impact factor:   3.466


  7 in total

Review 1.  Organization of restriction-modification systems.

Authors:  G G Wilson
Journal:  Nucleic Acids Res       Date:  1991-05-25       Impact factor: 16.971

2.  The specificity of sty SKI, a type I restriction enzyme, implies a structure with rotational symmetry.

Authors:  P H Thorpe; D Ternent; N E Murray
Journal:  Nucleic Acids Res       Date:  1997-05-01       Impact factor: 16.971

Review 3.  Biology of DNA restriction.

Authors:  T A Bickle; D H Krüger
Journal:  Microbiol Rev       Date:  1993-06

4.  A deletion mutant of the type IC restriction endonuclease EcoR1241 expressing a novel DNA specificity.

Authors:  A Abadjieva; J Patel; M Webb; V Zinkevich; K Firman
Journal:  Nucleic Acids Res       Date:  1993-09-25       Impact factor: 16.971

5.  Increased protein flexibility leads to promiscuous protein--DNA interactions in type IC restriction-modification systems.

Authors:  M Gubler; T A Bickle
Journal:  EMBO J       Date:  1991-04       Impact factor: 11.598

6.  Recombination of constant and variable modules alters DNA sequence recognition by type IC restriction-modification enzymes.

Authors:  M Gubler; D Braguglia; J Meyer; A Piekarowicz; T A Bickle
Journal:  EMBO J       Date:  1992-01       Impact factor: 11.598

7.  Macroevolution by transposition: drastic modification of DNA recognition by a type I restriction enzyme following Tn5 transposition.

Authors:  J Meister; M MacWilliams; P Hübner; H Jütte; E Skrzypek; A Piekarowicz; T A Bickle
Journal:  EMBO J       Date:  1993-12       Impact factor: 11.598

  7 in total

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