Literature DB >> 2550747

Regulation of thymidine kinase activity in mouse L cells biochemically transformed by varicella-zoster virus.

K Shiraki1, H Mori, Y Hayakawa, K Yamanishi, M Takahashi.   

Abstract

Regulation of thymidine kinase (TK) activity was examined in L(O)c133 and L(H3) cells carrying varicella-zoster virus-TK gene. TK activity of L(O)c133 cells was similarly high in either medium but that of L(H3) cells was high in HAT medium and low in non-HAT medium. Cell growth was well correlated with TK activities of L(O)c133 and L(H3) cells in medium conditions. Regulation of the TK gene in L cells carrying the VZV-TK gene is discussed.

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Year:  1989        PMID: 2550747     DOI: 10.1111/j.1348-0421.1989.tb02020.x

Source DB:  PubMed          Journal:  Microbiol Immunol        ISSN: 0385-5600            Impact factor:   1.955


  1 in total

1.  Human herpesvirus 8-encoded thymidine kinase and phosphotransferase homologues confer sensitivity to ganciclovir.

Authors:  J S Cannon; F Hamzeh; S Moore; J Nicholas; R F Ambinder
Journal:  J Virol       Date:  1999-06       Impact factor: 5.103

  1 in total

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