Literature DB >> 25505860

Profile of epilepsy in a regional hospital in Al qassim, saudi arabia.

Nermin A Hamdy1, Mohammad Jawad Alamgir2, El Gamri E Mohammad3, Mahmoud H Khedr1, Shafat Fazili3.   

Abstract

INTRODUCTION: Epilepsy is a diverse set of chronic neurological disorders characterized by seizures. It is one of the most common of the serious neurological disorders. About 3% of people will be diagnosed with epilepsy at some time in their lives.
OBJECTIVES: We aimed to address the commonest types of seizures, their aetiologies, EEG and neuroimaging results and prognosis of patients presented to neurology services of the King Fahad Specialist Hospital- AlQassim (KFSH).
METHODOLOGY: In this retrospective epidemiological study we investigated the medical records of patients with epilepsy, who attended the neurology services of KFSH, during the study period (26/10/2011-26/4/2012).
RESULTS: The study included 341 patients; 189 (55.4%) males and 152 (44.6%) females. Their ages ranged between 12 and 85 years (mean ± SD = 31±16.9). The majority of patients had Generalised Tonic Clonic Seizures (76.2%), followed by Complex Partial Seizures (7.6%). 73% of our patients had idiopathic epilepsy. The commonest causes for symptomatic epilepsy were Cerebro Vascular Accidents and Head trauma. Hemiplegia, mental retardation and psychiatric illness were the commonest comorbidity. 69.3% of patients had controlled seizures. Patients with idiopathic epilepsy were significantly controlled than patients with symptomatic epilepsy (P=0.01), and those using one Anti Epileptic Drug were significantly controlled compared to patients using polytherapy (P=0.0001) there was no significant relation between controlled seizure and duration of illness or hospitalization or EEG changes.
CONCLUSION: Seizure types, aetiology, drug therapy, Comorbidities and outcome in a tertiary care hospital in Saudi Arabia are similar to previous local and international studies. 35.3% of patients were hospitalized, higher rates than previous studies. Seizure control was better in generalized seizures and idiopathic epilepsy compared to complex partial seizures or partial seizures with secondary generalization and symptomatic epilepsy.

Entities:  

Keywords:  Saudi Arabia; epidemiology; epilepsy; seizures

Year:  2014        PMID: 25505860      PMCID: PMC4257360          DOI: 10.12816/0023977

Source DB:  PubMed          Journal:  Int J Health Sci (Qassim)        ISSN: 1658-3639


  35 in total

1.  Epilepsy in a remote area of southern Sudan.

Authors:  M T Perenchio; M Caldognetto; E Makender; S Qasim
Journal:  Trop Doct       Date:  2004-10       Impact factor: 0.731

Review 2.  Seizure recurrence after antiepileptic drug withdrawal and the implications for driving: further results from the MRC Antiepileptic Drug Withdrawal Study and a systematic review.

Authors:  Laura J Bonnett; Arif Shukralla; Catrin Tudur-Smith; Paula R Williamson; Antony G Marson
Journal:  J Neurol Neurosurg Psychiatry       Date:  2011-01-13       Impact factor: 10.154

3.  Randomised study of antiepileptic drug withdrawal in patients in remission. Medical Research Council Antiepileptic Drug Withdrawal Study Group.

Authors: 
Journal:  Lancet       Date:  1991-05-18       Impact factor: 79.321

4.  Prevalence of epilepsy in Kelibia, Tunisia.

Authors:  N Attia-Romdhane; A Mrabet; M Ben Hamida
Journal:  Epilepsia       Date:  1993 Nov-Dec       Impact factor: 5.864

Review 5.  Genetics of epilepsy and relevance to current practice.

Authors:  Roberto Michelucci; Elena Pasini; Patrizia Riguzzi; Lilia Volpi; Emanuela Dazzo; Carlo Nobile
Journal:  Curr Neurol Neurosci Rep       Date:  2012-08       Impact factor: 5.081

Review 6.  Neuropsychological effects of epilepsy and antiepileptic drugs.

Authors:  P Kwan; M J Brodie
Journal:  Lancet       Date:  2001-01-20       Impact factor: 79.321

7.  An estimate of the prevalence of psychogenic non-epileptic seizures.

Authors:  S R Benbadis; W Allen Hauser
Journal:  Seizure       Date:  2000-06       Impact factor: 3.184

Review 8.  A systematic review of the epidemiology of epilepsy in Arab countries.

Authors:  Hani T S Benamer; Donald G Grosset
Journal:  Epilepsia       Date:  2009-04-06       Impact factor: 5.864

9.  Psychiatric comorbidity in epilepsy: a population-based analysis.

Authors:  Jose F Tellez-Zenteno; Scott B Patten; Nathalie Jetté; Jeanne Williams; Samuel Wiebe
Journal:  Epilepsia       Date:  2007-07-28       Impact factor: 5.864

10.  Neuroepidemiology of epilepsy in northwest India.

Authors:  Surender Kumar Pal; Krishan Sharma; Sudesh Prabhakar; Ashish Pathak
Journal:  Ann Neurosci       Date:  2010-10
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  3 in total

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Journal:  SAGE Open Med       Date:  2022-05-23

2.  Prognostic factors for epilepsy following first febrile seizure in Saudi children.

Authors:  Abdullah I Almojali; Anwar E Ahmed; Muhammed Y Bagha
Journal:  Ann Saudi Med       Date:  2017 Nov-Dec       Impact factor: 1.526

3.  Prevalence and biopsychosocial factors associated with treatment adherence among people with epilepsy in a tertiary care hospital in Riyadh, Saudi Arabia.

Authors:  Amani S Almwled; Abdulkarim O Almuhaydili; Saqr M Altamimi; Muhannad A Alzahrani; Rodhan K Alnahdi; Saad B Almotairi; Bandar N Aljafen; Fahad D Alosaimi
Journal:  Neurosciences (Riyadh)       Date:  2022-04       Impact factor: 0.735

  3 in total

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