Literature DB >> 2550577

The polypeptide of Mr 14,000 of porcine transmissible gastroenteritis virus: gene assignment and intracellular location.

D J Garwes1, F Stewart, P Britton.   

Abstract

Synthetic oligopeptides, corresponding to an amino acid sequence encoded by a potential Mr 9000 product's open reading frame (ORF-4) at the 3' terminus of the transmissible gastroenteritis virus genome, were used to generate rabbit antiserum. These antibodies produced immune complexes with an Mr 14,000 (14K) polypeptide in infected cells. The 14K product was shown by immune fluorescence to become associated with the cell nucleus, correlating with the onset of nuclear vacuolation, and suggesting a role in pathogenesis for the ORF-4 gene.

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Year:  1989        PMID： 2550577     DOI： 10.1099/0022-1317-70-9-2495

Source DB:  PubMed          Journal:  J Gen Virol        ISSN： 0022-1317            Impact factor:   3.891


  13 in total

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Authors:  H Vennema; L Heijnen; P J Rottier; M C Horzinek; W J Spaan
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2.  Structural maturation of the transmissible gastroenteritis coronavirus.

Authors:  I J Salanueva; J L Carrascosa; C Risco
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3.  Sequence comparison of porcine respiratory coronavirus isolates reveals heterogeneity in the S, 3, and 3-1 genes.

Authors:  E M Vaughn; P G Halbur; P S Paul
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4.  Genetic analysis of porcine respiratory coronavirus, an attenuated variant of transmissible gastroenteritis virus.

Authors:  R D Wesley; R D Woods; A K Cheung
Journal:  J Virol       Date:  1991-06       Impact factor: 5.103

5.  Molecular cloning and phylogenetic analysis of ORF7 region of chinese isolate TH-98 from transmissible gastroenteritis virus.

Authors:  Jie-Chao Yin; Xiao-Feng Ren; Yi-Jing Li
Journal:  Virus Genes       Date:  2005-05       Impact factor: 2.332

6.  Transmissible gastroenteritis coronavirus gene 7 is not essential but influences in vivo virus replication and virulence.

Authors:  Javier Ortego; Isabel Sola; Fernando Almazán; Juan E Ceriani; Cristina Riquelme; Monica Balasch; Juan Plana; Luis Enjuanes
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Review 7.  The molecular biology of coronaviruses.

Authors:  M M Lai; D Cavanagh
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8.  The cloning and sequencing of the virion protein genes from a British isolate of porcine respiratory coronavirus: comparison with transmissible gastroenteritis virus genes.

Authors:  P Britton; K L Mawditt; K W Page
Journal:  Virus Res       Date:  1991-11       Impact factor: 3.303

9.  Sequence of the S gene from a virulent British field isolate of transmissible gastroenteritis virus.

Authors:  P Britton; K W Page
Journal:  Virus Res       Date:  1990-12       Impact factor: 3.303

10.  TGEV corona virus ORF4 encodes a membrane protein that is incorporated into virions.

Authors:  M Godet; R L'Haridon; J F Vautherot; H Laude
Journal:  Virology       Date:  1992-06       Impact factor: 3.616
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