| Literature DB >> 25504939 |
B A McCrossan1, C J McMahon1, K P Walsh1.
Abstract
The aim of catheter intervention for vascular stenosis is the restoration of lumen area and optimization of distal blood flow. In pediatric practice, this has traditionally been a compromise between less effective balloon angioplasty and bare metal stent insertion with its attendant limitations of size. Bioabsorbable stents offer short-term relief of stenosis, radial support of the healing lesion, return of endothelial function and crucially, in children, the potential for long-term growth. Initial experience, in pediatric practice, with metal-based bioabsorbable stents was relatively disappointing with frequent restenosis secondary to early reabsorption. Design modifications resulting in polymer-based, drug eluting, bioabsorbable vascular scaffolds (BVS) have reportedly overcome some of these faults. We describe the first reported use of a drug eluting BVS in three patients with: (1) A newborn with severe right pulmonary artery (RPA) stensosis post repair of type two common arterial trunk. (2) A child with pulmonary atresia/ventricular septal defect (VSD) and major aorto-pulmonary collateral arteries (MAPCAs), and (3) An infant with severe left pulmonary artery (LPA) stenosis in the setting of an LPA sling.Entities:
Keywords: bioabsorbable; congenital heart disease; pediatrics; stent; stent restenosis
Mesh:
Substances:
Year: 2015 PMID: 25504939 DOI: 10.1002/ccd.25768
Source DB: PubMed Journal: Catheter Cardiovasc Interv ISSN: 1522-1946 Impact factor: 2.692