Jee Eun Park1,2, Jun-Young Lee1,3, Byung-Soo Kim4, Ki Woong Kim1,5,6, Song Hwa Chae7, Maeng Je Cho1,2. 1. Department of Psychiatry and Behavioral Science, Seoul National University College of Medicine, Seoul, South Korea. 2. Department of Neuropsychiatry, Seoul National University Hospital, Seoul, South Korea. 3. Department of Neuropsychiatry, Seoul Metropolitan Boramae Medical Center, Seoul, South Korea. 4. Department of Psychiatry, Kyungpook National University Medical Center, Kyungpook National University School of Medicine, Daegu, South Korea. 5. Department of Neuropsychiatry, Seoul National University Bundang Hospital, Seongnam, South Korea. 6. Department of Brain and Cognitive Science, Seoul National University College of Natural Sciences, Seoul, South Korea. 7. Department of Psychology, Sungshin Women's University, Seoul, South Korea.
Abstract
OBJECTIVE: To investigate the natural course of depressive symptoms among community-dwelling elderly over 5 years. Rates and correlates of the incidence and the persistence of late-life depression were examined. METHODS: A total of 701 elderly people 65 years of age or older without dementia at baseline were included in this study. The association between categorically defined late-life depression (score of ≥ 8 on the Korean version of the Geriatric Depression Scale-Short Form) and possible lifestyle and clinical risk factors, including physical activity assessed with a modified Korean version of the International Physical Activity Questionnaire (IPAQ) and transformed into weekly Metabolic Equivalent Task (MET) values, was longitudinally investigated using multiple logistic regression analyses. Adjustment was done with sociodemographic variables, chronic medical illnesses, and cognitive dysfunction. RESULTS: During the 5-year follow-up, 74 (26.5%) of the non-depressed elderly developed depression, whereas 30 (49.2%) of the depressed elderly experienced persistent depression. Above-moderate baseline physical activity was independently associated with decreased incidence and persistence rates of late-life depression (adjusted odds ratio (AOR) = 0.44, 95% confidence interval (CI) = 0.22-0.85; AOR = 0.17, 95% CI = 0.03-0.92, respectively), whereas mild physical activity was not. Conversely, poorer executive function also predicted 5-year incident depression (AOR = 0.93, 95% CI = 0.89-0.98) but not persistent depression. CONCLUSION: This study suggests that a minimum of moderate physical activity is related to both emergent and persistent depression in elderly individuals. Research with an extended follow-up period and a shorter inter-assessment interval is needed to confirm this result.
OBJECTIVE: To investigate the natural course of depressive symptoms among community-dwelling elderly over 5 years. Rates and correlates of the incidence and the persistence of late-life depression were examined. METHODS: A total of 701 elderly people 65 years of age or older without dementia at baseline were included in this study. The association between categorically defined late-life depression (score of ≥ 8 on the Korean version of the Geriatric Depression Scale-Short Form) and possible lifestyle and clinical risk factors, including physical activity assessed with a modified Korean version of the International Physical Activity Questionnaire (IPAQ) and transformed into weekly Metabolic Equivalent Task (MET) values, was longitudinally investigated using multiple logistic regression analyses. Adjustment was done with sociodemographic variables, chronic medical illnesses, and cognitive dysfunction. RESULTS: During the 5-year follow-up, 74 (26.5%) of the non-depressed elderly developed depression, whereas 30 (49.2%) of the depressed elderly experienced persistent depression. Above-moderate baseline physical activity was independently associated with decreased incidence and persistence rates of late-life depression (adjusted odds ratio (AOR) = 0.44, 95% confidence interval (CI) = 0.22-0.85; AOR = 0.17, 95% CI = 0.03-0.92, respectively), whereas mild physical activity was not. Conversely, poorer executive function also predicted 5-year incident depression (AOR = 0.93, 95% CI = 0.89-0.98) but not persistent depression. CONCLUSION: This study suggests that a minimum of moderate physical activity is related to both emergent and persistent depression in elderly individuals. Research with an extended follow-up period and a shorter inter-assessment interval is needed to confirm this result.
Authors: Hyun Woong Roh; Chang Hyung Hong; Yunhwan Lee; Byoung Hoon Oh; Kang Soo Lee; Ki Jung Chang; Dae Ryong Kang; Jinhee Kim; SooJin Lee; Joung Hwan Back; Young Ki Chung; Ki Young Lim; Jai Sung Noh; Dongsoo Kim; Sang Joon Son Journal: PLoS One Date: 2015-07-14 Impact factor: 3.240
Authors: Caitlin Worrall; Michelle I Jongenelis; Peter M McEvoy; Ben Jackson; Robert U Newton; Simone Pettigrew Journal: Front Public Health Date: 2020-11-12
Authors: Myrthe C Bruin; Hannie C Comijs; Rob M Kok; Roos C Van der Mast; Julia F Van den Berg Journal: Int J Geriatr Psychiatry Date: 2018-04-24 Impact factor: 3.485