| Literature DB >> 25501942 |
Fabian Sievers1, Desmond G Higgins.
Abstract
Clustal Omega is a package for making multiple sequence alignments of amino acid or nucleotide sequences, quickly and accurately. It is a complete upgrade and rewrite of earlier Clustal programs. This unit describes how to run Clustal Omega interactively from a command line, although it can also be run online from several sites. The unit describes a basic protocol for taking a set of unaligned sequences and producing a full alignment. There are also protocols for using an external HMM or iteration to help improve an alignment.Keywords: Clustal Omega; HMM; hidden Markov model; iteration; multiple sequence alignment
Mesh:
Year: 2014 PMID: 25501942 DOI: 10.1002/0471250953.bi0313s48
Source DB: PubMed Journal: Curr Protoc Bioinformatics ISSN: 1934-3396