Irene A Burger1, Moritz C Wurnig2, Anton S Becker2, David Kenkel2, Gaspar Delso3, Patrick Veit-Haibach4, Andreas Boss2. 1. Institute of Diagnostic and Interventional Radiology, University Hospital Zurich, Zurich, Switzerland Department of Nuclear Medicine, University Hospital Zurich, Zurich, Switzerland; and irene.burger@usz.ch. 2. Institute of Diagnostic and Interventional Radiology, University Hospital Zurich, Zurich, Switzerland. 3. GE Healthcare, Waukesha, Wisconsin. 4. Institute of Diagnostic and Interventional Radiology, University Hospital Zurich, Zurich, Switzerland Department of Nuclear Medicine, University Hospital Zurich, Zurich, Switzerland; and.
Abstract
UNLABELLED: It was the aim of this study to implement an algorithm modifying Dixon-based MR imaging datasets for attenuation correction in hybrid PET/MR imaging with a multiacquisition variable resonance image combination (MAVRIC) sequence to reduce metal artifacts. METHODS: After ethics approval, in 8 oncologic patients with dental implants data were acquired in a trimodality setup with PET/CT and MR imaging. The protocol included a whole-body 3-dimensional dual gradient-echo sequence (Dixon) used for MR imaging-based PET attenuation correction and a high-resolution MAVRIC sequence, applied in the oral area compromised by dental implants. An algorithm was implemented correcting the Dixon-based μ maps using the MAVRIC in areas of Dixon signal voids. The artifact size of the corrected μ maps was compared with the uncorrected MR imaging μ maps. RESULTS: The algorithm was robust in all patients. There was a significant reduction in mean artifact size of 70.5% between uncorrected and corrected μ maps from 697 ± 589 mm(2) to 202 ± 119 mm(2) (P = 0.016). CONCLUSION: The proposed algorithm could improve MR imaging-based attenuation correction in critical areas, when standard attenuation correction is hampered by metal artifacts, using a MAVRIC.
UNLABELLED: It was the aim of this study to implement an algorithm modifying Dixon-based MR imaging datasets for attenuation correction in hybrid PET/MR imaging with a multiacquisition variable resonance image combination (MAVRIC) sequence to reduce metal artifacts. METHODS: After ethics approval, in 8 oncologic patients with dental implants data were acquired in a trimodality setup with PET/CT and MR imaging. The protocol included a whole-body 3-dimensional dual gradient-echo sequence (Dixon) used for MR imaging-based PET attenuation correction and a high-resolution MAVRIC sequence, applied in the oral area compromised by dental implants. An algorithm was implemented correcting the Dixon-based μ maps using the MAVRIC in areas of Dixon signal voids. The artifact size of the corrected μ maps was compared with the uncorrected MR imaging μ maps. RESULTS: The algorithm was robust in all patients. There was a significant reduction in mean artifact size of 70.5% between uncorrected and corrected μ maps from 697 ± 589 mm(2) to 202 ± 119 mm(2) (P = 0.016). CONCLUSION: The proposed algorithm could improve MR imaging-based attenuation correction in critical areas, when standard attenuation correction is hampered by metal artifacts, using a MAVRIC.
Authors: Claes N Ladefoged; Flemming L Andersen; Sune H Keller; Thomas Beyer; Ian Law; Liselotte Højgaard; Sune Darkner; Francois Lauze Journal: J Med Imaging (Bellingham) Date: 2015-06-09
Authors: Urs J Muehlematter; Hannes W Nagel; Anton Becker; Julian Mueller; Kerstin N Vokinger; Felipe de Galiza Barbosa; Edwin E G T Ter Voert; Patrick Veit-Haibach; Irene A Burger Journal: EJNMMI Res Date: 2018-05-31 Impact factor: 3.138
Authors: Francesca De Luca; Martin Bolin; Lennart Blomqvist; Cecilia Wassberg; Heather Martin; Anna Falk Delgado Journal: BMC Med Imaging Date: 2020-11-25 Impact factor: 1.930