Yong Wei1, Baozhen Qi2, Juan Xu3, Genqing Zhou3, Songwen Chen3, Ping Ouyang2, Shaowen Liu4. 1. Department of Cardiology, Shanghai Songjiang Central Hospital, Shanghai, China; Department of Cardiology, Shanghai First People's Hospital, Shanghai Jiao Tong University, Shanghai 200800, China. 2. Department of Cardiology, Shanghai Songjiang Central Hospital, Shanghai, China. 3. Department of Cardiology, Shanghai First People's Hospital, Shanghai Jiao Tong University, Shanghai 200800, China. 4. Department of Cardiology, Shanghai First People's Hospital, Shanghai Jiao Tong University, Shanghai 200800, China. Electronic address: shaowen.liu@hotmail.com.
Abstract
BACKGROUND: It was not understood whether age- and sex-related differences were apparent in lipid profiles among acute myocardial infarction (AMI) patients in China. OBJECTIVES: To investigate lipid abnormalities in such AMI patients. METHODS: A retrospective analysis of 1213 patients hospitalized with a first AMI between May 2007 and July 2011. RESULTS: Our data indicated that, compared with the elderly, the nonelderly tended to have higher low-density lipoprotein cholesterol (LDL), total cholesterol (TC), and non-high-density lipoprotein cholesterol (N-HDL) for both males and females. There was significant difference in LDL among various age groups (P < .001): LDL levels in the 50-59 and 60-69 year age groups were higher than those in 70-79 and 80-89 year age groups. Compared with males, females tended to have higher LDL in both the 50-59 and 60-69 year age groups. There was no difference in HDL among various age groups for female AMI patients, but there was significance for males. Compared with males, females had higher HDL in 40-49, 50-59, 60-69, and 70-79 year age groups, respectively. Among various age groups, there was significant difference in triglycerides (TG) for male AMI patients, but no difference in TG for females. The levels of TG were higher in 40-49, 50-59, and 60-69 year age groups than those in 70-79, 80-89, and ≥90 year age groups, respectively, for males. Isolated low HDL (low HDL + normal LDL + normal TG) was the most common type of combined dyslipidemia for male elderly (31.4%), male nonelderly (22.9%), and female elderly (19.2%) patients. CONCLUSION: We concluded that there was age- and sex-related difference in lipid profiles among AMI patients, with more prevalent dyslipidemia in the nonelderly than the elderly. Perimenopausal women were prone to higher LDL, and low HDL was prevalent among AMI patients in East China.
BACKGROUND: It was not understood whether age- and sex-related differences were apparent in lipid profiles among acute myocardial infarction (AMI) patients in China. OBJECTIVES: To investigate lipid abnormalities in such AMI patients. METHODS: A retrospective analysis of 1213 patients hospitalized with a first AMI between May 2007 and July 2011. RESULTS: Our data indicated that, compared with the elderly, the nonelderly tended to have higher low-density lipoprotein cholesterol (LDL), total cholesterol (TC), and non-high-density lipoprotein cholesterol (N-HDL) for both males and females. There was significant difference in LDL among various age groups (P < .001): LDL levels in the 50-59 and 60-69 year age groups were higher than those in 70-79 and 80-89 year age groups. Compared with males, females tended to have higher LDL in both the 50-59 and 60-69 year age groups. There was no difference in HDL among various age groups for female AMI patients, but there was significance for males. Compared with males, females had higher HDL in 40-49, 50-59, 60-69, and 70-79 year age groups, respectively. Among various age groups, there was significant difference in triglycerides (TG) for male AMI patients, but no difference in TG for females. The levels of TG were higher in 40-49, 50-59, and 60-69 year age groups than those in 70-79, 80-89, and ≥90 year age groups, respectively, for males. Isolated low HDL (low HDL + normal LDL + normal TG) was the most common type of combined dyslipidemia for male elderly (31.4%), male nonelderly (22.9%), and female elderly (19.2%) patients. CONCLUSION: We concluded that there was age- and sex-related difference in lipid profiles among AMI patients, with more prevalent dyslipidemia in the nonelderly than the elderly. Perimenopausal women were prone to higher LDL, and low HDL was prevalent among AMI patients in East China.