| Literature DB >> 25499805 |
Vera Ortseifen1, Anika Winkler2, Andreas Albersmeier2, Sergej Wendler3, Alfred Pühler3, Jörn Kalinowski4, Christian Rückert5.
Abstract
Here we report the complete and finished genome sequence of Streptomyces glaucescens GLA.O (DSM 40922), a natural producer of the alpha-glucosidase inhibitor acarbose, which is used in the treatment of type-2 diabetes mellitus. The genome of S. glaucescens GLA.O consists of two replicons, the chromosome with a size of 7,453,200bp and a G+C content of 73.0% as well as a plasmid named pSglau1 with a size of 170,574bp and a G+C content of 69.06%.Entities:
Keywords: 5′-hydroxystreptomycin; Acarbose production; Genome sequence; Streptomyces; Tetracenomycin C
Mesh:
Year: 2014 PMID: 25499805 DOI: 10.1016/j.jbiotec.2014.11.036
Source DB: PubMed Journal: J Biotechnol ISSN: 0168-1656 Impact factor: 3.307