Mika Baba1, Isseki Maeda2, Tatsuya Morita3, Takayuki Hisanaga4, Tatsuhiko Ishihara5, Tomoyuki Iwashita6, Keisuke Kaneishi7, Shohei Kawagoe8, Toshiyuki Kuriyama9, Takashi Maeda10, Ichiro Mori11, Nobuhisa Nakajima12, Tomohiro Nishi13, Hiroki Sakurai14, Satofumi Shimoyama15, Takuya Shinjo16, Hiroto Shirayama17, Takeshi Yamada18, Shigeki Ono19, Taketoshi Ozawa20, Ryo Yamamoto21, Satoru Tsuneto22. 1. Department of Palliative Care, Saito Yukoukai Hospital, Ibaragi, Osaka, Japan. Electronic address: baba@saito-yukoukai-hp.jp. 2. Department of Palliative Medicine, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan. 3. Palliative and Supportive Care Division, Seirei Mikatahara General Hospital, Hamamatsu City, Shizuoka, Japan. 4. Tsukuba Medical Center Foundation, Tsukuba, Ibaraki, Japan. 5. Palliative Care Department, Okayama Saiseikai General Hospital, Okayama City, Okayama, Japan. 6. Matsue City Hospital, Matsue City, Shimane, Japan. 7. Department of Palliative Care Unit, JCHO Tokyo Shinjuku Medical Center, Shinjuku, Tokyo, Japan. 8. Aozora Clinic, Matsudo-city, Chiba, Japan. 9. Department of Palliative Medicine, Wakayama Medical University Hospital Oncology Center, Kimiidera, Wakayama, Japan. 10. Department of Palliative Care, Tokyo Metropolitan Cancer and Infectious Disease Center, Komagome Hospital, Bunkyo-ku, Tokyo, Japan. 11. Gratia Hospital Hospice, Mino, Osaka, Japan. 12. Department of Palliative Medicine, Graduate School of Medicine, Tohoku University, Sendai, Miyagi, Japan. 13. Kawasaki Comprehensive Care Center, Kawasaki Municipal Ida Hospital, Nakahara-ku, Kanagawa, Japan. 14. Department of Palliative Care, St. Luke's International Hospital, Chuo-ku, Tokyo, Japan. 15. Department of Palliative Care, Aichi Cancer Center Hospital, Chikusa-ku, Nagoya, Japan. 16. Shinjo Clinic, Kobe, Hyogo, Japan. 17. Iryouhoujinn Takumikai Osaka Kita Homecare Clinic, Osaka City, Osaka, Japan. 18. Department of Gastrointestinal and Hepatobiliary-Pancreatic Surgery, Nippon Medical School, Bunkyo-ku, Tokyo, Japan. 19. Division of Palliative Medicine, Shizuoka Cancer Center Hospital, Suntou-gun, Shizuoka, Japan. 20. Megumi Zaitaku Clinic, Yokohama-shi, Kanagawa, Japan. 21. Department of Palliative Medicine, Saku Central Hospital Advanced Care Center, Saku-shi, Nagano, Japan. 22. Department of Multidisciplinary Cancer Treatment, Graduate School of Medicine, Kyoto University, Sakyo-ku, Kyoto, Japan.
Abstract
CONTEXT: Accurate prognostic information in palliative care settings is needed for patients to make decisions and set goals and priorities. The Prognosis Palliative Care Study (PiPS) predictor models were presented in 2011, but have not yet been fully validated by other research teams. OBJECTIVES: The primary aim of this study is to examine the accuracy and to validate the modified PiPS (using physician-proxy ratings of mental status instead of patient interviews) in three palliative care settings, namely palliative care units, hospital-based palliative care teams, and home-based palliative care services. METHODS: This multicenter prospective cohort study was conducted in 58 palliative care services including 16 palliative care units, 19 hospital-based palliative care teams, and 23 home-based palliative care services in Japan from September 2012 through April 2014. RESULTS: A total of 2426 subjects were recruited. For reasons including lack of followup and missing variables (primarily blood examination data), we obtained analyzable data from 2212 and 1257 patients for the modified PiPS-A and PiPS-B, respectively. In all palliative care settings, both the modified PiPS-A and PiPS-B identified three risk groups with different survival rates (P<0.001). The absolute agreement ranged from 56% to 60% in the PiPS-A model and 60% to 62% in the PiPS-B model. CONCLUSION: The modified PiPS was successfully validated and can be useful in palliative care units, hospital-based palliative care teams, and home-based palliative care services.
CONTEXT: Accurate prognostic information in palliative care settings is needed for patients to make decisions and set goals and priorities. The Prognosis Palliative Care Study (PiPS) predictor models were presented in 2011, but have not yet been fully validated by other research teams. OBJECTIVES: The primary aim of this study is to examine the accuracy and to validate the modified PiPS (using physician-proxy ratings of mental status instead of patient interviews) in three palliative care settings, namely palliative care units, hospital-based palliative care teams, and home-based palliative care services. METHODS: This multicenter prospective cohort study was conducted in 58 palliative care services including 16 palliative care units, 19 hospital-based palliative care teams, and 23 home-based palliative care services in Japan from September 2012 through April 2014. RESULTS: A total of 2426 subjects were recruited. For reasons including lack of followup and missing variables (primarily blood examination data), we obtained analyzable data from 2212 and 1257 patients for the modified PiPS-A and PiPS-B, respectively. In all palliative care settings, both the modified PiPS-A and PiPS-B identified three risk groups with different survival rates (P<0.001). The absolute agreement ranged from 56% to 60% in the PiPS-A model and 60% to 62% in the PiPS-B model. CONCLUSION: The modified PiPS was successfully validated and can be useful in palliative care units, hospital-based palliative care teams, and home-based palliative care services.
Authors: David Hui; Carlos Eduardo Paiva; Egidio G Del Fabbro; Christopher Steer; Jane Naberhuis; Marianne van de Wetering; Paz Fernández-Ortega; Tatsuya Morita; Sang-Yeon Suh; Eduardo Bruera; Masanori Mori Journal: Support Care Cancer Date: 2019-03-13 Impact factor: 3.603
Authors: Patrick Stone; Anastasia Kalpakidou; Chris Todd; Jane Griffiths; Vaughan Keeley; Karen Spencer; Peter Buckle; Dori-Anne Finlay; Victoria Vickerstaff; Rumana Z Omar Journal: Health Technol Assess Date: 2021-05 Impact factor: 4.014
Authors: Victoria Louise Reid; Rachael McDonald; Amara Callistus Nwosu; Stephen R Mason; Chris Probert; John E Ellershaw; Séamus Coyle Journal: PLoS One Date: 2017-04-06 Impact factor: 3.240
Authors: Anastasia K Kalpakidou; Chris Todd; Vaughan Keeley; Jane Griffiths; Karen Spencer; Victoria Vickerstaff; Rumana Z Omar; Patrick Stone Journal: BMC Palliat Care Date: 2018-08-13 Impact factor: 3.234