Literature DB >> 25497324

Cross-sections for (p,x) reactions on natural chromium for the production of (52,52m,54)Mn radioisotopes.

A Lake Wooten1, Benjamin C Lewis2, Suzanne E Lapi3.   

Abstract

The production of positron-emitting isotopes of manganese is potentially important for developing contrast agents for dual-modality positron emission tomography and magnetic resonance (PET/MR) imaging, as well as for in vivo imaging of the biodistribution and toxicity of manganese. The decay properties of (52)Mn make it an excellent candidate for these applications, and it can easily be produced by bombardment of a chromium target with protons or deuterons from a low-energy biomedical cyclotron. Several parameters that are essential to this mode of production—target thickness, beam energy, beam current, and bombardment time—depend heavily on the availability of reliable, reproducible cross-section data. This work contributes to the routine production of (52g)Mn for biomedical research by contributing experimental cross-sections for natural chromium ((nat)Cr) targets for the (nat)Cr(p,x)(52g)Mn reaction, as well as for the production of the radiocontaminants (52m,54)Mn.
Copyright © 2014. Published by Elsevier Ltd.

Entities:  

Keywords:  (52)Mn; (52)mMn; (54)Mn; Cross-section; Isotope production; PET isotopes; Radiometal; Solid target

Mesh：

Substances：

Year:  2014        PMID： 25497324      PMCID： PMC4910688          DOI： 10.1016/j.apradiso.2014.12.001

Source DB:  PubMed          Journal:  Appl Radiat Isot        ISSN： 0969-8043            Impact factor:   1.513


  5 in total

1.  A new and simple calibration-independent method for measuring the beam energy of a cyclotron.

Authors:  Katherine Gagnon; Mikael Jensen; Helge Thisgaard; Julia Publicover; Suzanne Lapi; Steve A McQuarrie; Thomas J Ruth
Journal:  Appl Radiat Isot       Date:  2011-01       Impact factor: 1.513

2.  52Cr(p,n)52Mng,m and 52Cr(d,2n)52Mng,m excitation functions.

Authors: 
Journal:  Phys Rev C Nucl Phys       Date:  1987-06

3.  Exposure rate constants and lead shielding values for over 1,100 radionuclides.

Authors:  David S Smith; Michael G Stabin
Journal:  Health Phys       Date:  2012-03       Impact factor: 1.316

4.  Cyclotron production of (99m)Tc: experimental measurement of the (100)Mo(p,x)(99)Mo, (99m)Tc and (99g)Tc excitation functions from 8 to 18 MeV.

Authors:  Katherine Gagnon; François Bénard; Michael Kovacs; Thomas J Ruth; Paul Schaffer; John S Wilson; Steve A McQuarrie
Journal:  Nucl Med Biol       Date:  2011-05-06       Impact factor: 2.408

5.  Manganese-52 positron emission tomography tracer characterization and initial results in phantoms and in vivo.

Authors:  Geoffrey J Topping; Paul Schaffer; Cornelia Hoehr; Thomas J Ruth; Vesna Sossi
Journal:  Med Phys       Date:  2013-04       Impact factor: 4.071
  5 in total
  8 in total

1.  Uptake and retention of manganese contrast agents for PET and MRI in the rodent brain.

Authors:  Christina L Brunnquell; Reinier Hernandez; Stephen A Graves; Ivy Smit-Oistad; Robert J Nickles; Weibo Cai; M Elizabeth Meyerand; Masatoshi Suzuki
Journal:  Contrast Media Mol Imaging       Date:  2016-07-11       Impact factor: 3.161

2.  Novel Preparation Methods of (52)Mn for ImmunoPET Imaging.

Authors:  Stephen A Graves; Reinier Hernandez; Jesper Fonslet; Christopher G England; Hector F Valdovinos; Paul A Ellison; Todd E Barnhart; Dennis R Elema; Charles P Theuer; Weibo Cai; Robert J Nickles; Gregory W Severin
Journal:  Bioconjug Chem       Date:  2015-09-10       Impact factor: 4.774

3.  Nuclear excitation functions of proton-induced reactions (Ep = 35 - 90 MeV) from Fe, Cu, and Al.

Authors:  Stephen A Graves; Paul A Ellison; Todd E Barnhart; Hector F Valdovinos; Eva R Birnbaum; Francois M Nortier; Robert J Nickles; Jonathan W Engle
Journal:  Nucl Instrum Methods Phys Res B       Date:  2016-09-28       Impact factor: 1.377

4.  Biodistribution and PET Imaging of pharmacokinetics of manganese in mice using Manganese-52.

Authors:  A Lake Wooten; Tolulope A Aweda; Benjamin C Lewis; Rebecca B Gross; Suzanne E Lapi
Journal:  PLoS One       Date:  2017-03-17       Impact factor: 3.240

5.  Photonuclear production, chemistry, and in vitro evaluation of the theranostic radionuclide 47Sc.

Authors:  C Shaun Loveless; Lauren L Radford; Samuel J Ferran; Stacy L Queern; Matthew R Shepherd; Suzanne E Lapi
Journal:  EJNMMI Res       Date:  2019-05-16       Impact factor: 3.138

Review 6.  Manganese in PET imaging: Opportunities and challenges.

Authors:  Marie Brandt; Jens Cardinale; Ivo Rausch; Thomas L Mindt
Journal:  J Labelled Comp Radiopharm       Date:  2019-06-30       Impact factor: 1.921

7.  Characterization of actinide resin for separation of 51,52gMn from bulk target material.

Authors:  Kendall E Barrett; Eduardo Aluicio-Sarduy; Steffen Happel; Aeli P Olson; Christopher J Kutyreff; Paul A Ellison; Todd E Barnhart; Jonathan W Engle
Journal:  Nucl Med Biol       Date:  2021-03-03       Impact factor: 2.408

8.  A New Oxygen Containing Pyclen-Type Ligand as a Manganese(II) Binder for MRI and 52Mn PET Applications: Equilibrium, Kinetic, Relaxometric, Structural and Radiochemical Studies.

Authors:  Tibor Csupász; Dániel Szücs; Ferenc Krisztián Kálmán; Oldamur Hollóczki; Anikó Fekete; Dezső Szikra; Éva Tóth; Imre Tóth; Gyula Tircsó
Journal:  Molecules       Date:  2022-01-07       Impact factor: 4.411
  8 in total

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