Shokoufeh Bonakdaran1, Bita Kiafar2, Fatemeh Barazandeh Ahmadabadi1. 1. Endocrine Research Centre, Ghaem Hospital, Mashhad University of Medical Science, Mashhad, Iran. 2. Skin Ward, Emam Reza Hospital, Mashhad University of Medical Science, Mashhad, Iran.
Abstract
INTRODUCTION: Hirsutism is defined as the excessive male-pattern growth of hair in women. Hirsutism is often idiopathic or the consequence of polycystic ovary syndrome (PCOS). Insulin resistance is common in PCOS (especially in obese patients) but the association between insulin resistance and idiopathic hirsutism (IH) is not clear. The aim of this study was to investigate the rate of insulin resistance in IH, compared with healthy individuals and patients with PCOS. METHODS: The study included three groups, patients with idiopathic hirsutism, PCOS and healthy women. Each group included 30 non-obese women. Fasting blood sugar (FBS), insulin level and insulin resistance (estimated by the homeostasis model assessment [HOMA-IRIR]) were compared in the three groups. RESULTS: There was a significant difference between the age of the women with IH compared with two other groups. There were no significant difference in levels of serum insulin (P = 0.49, HOMA-IR (P = 0.47) and prevalence of insulin resistance (P = 0.07) in the three groups. The age-adjusted prevalence of insulin resistance was similar in the three groups. CONCLUSION: Insulin resistance was no more frequent in IH patients than in healthy control groups.
INTRODUCTION:Hirsutism is defined as the excessive male-pattern growth of hair in women. Hirsutism is often idiopathic or the consequence of polycystic ovary syndrome (PCOS). Insulin resistance is common in PCOS (especially in obesepatients) but the association between insulin resistance and idiopathic hirsutism (IH) is not clear. The aim of this study was to investigate the rate of insulin resistance in IH, compared with healthy individuals and patients with PCOS. METHODS: The study included three groups, patients with idiopathic hirsutism, PCOS and healthy women. Each group included 30 non-obesewomen. Fasting blood sugar (FBS), insulin level and insulin resistance (estimated by the homeostasis model assessment [HOMA-IRIR]) were compared in the three groups. RESULTS: There was a significant difference between the age of the women with IH compared with two other groups. There were no significant difference in levels of serum insulin (P = 0.49, HOMA-IR (P = 0.47) and prevalence of insulin resistance (P = 0.07) in the three groups. The age-adjusted prevalence of insulin resistance was similar in the three groups. CONCLUSION:Insulin resistance was no more frequent in IH patients than in healthy control groups.
Authors: Atefeh Krouni; Sedighe Forouhari; Bahia Namavarjahromi; Mohammad Hossein Dabbaghmanesh; Arezoo Shayan; Sara Sepasi; Atefeh Zare Journal: J Family Med Prim Care Date: 2017 Oct-Dec