Literature DB >> 25496070

Compounding diagnostic delays: a qualitative study of point-of-care testing in South Africa.

Nora Engel1, Malika Davids, Nadine Blankvoort, Nitika Pant Pai, Keertan Dheda, Madhukar Pai.   

Abstract

OBJECTIVES: Successful point-of-care (POC) testing (completion of test-and-treat cycle in one patient encounter) has immense potential to reduce diagnostic and treatment delays, and improve patient and public health outcomes. We explored what tests are done and how in public/private, rural/urban hospitals and clinics in South Africa and whether they can ensure successful POC testing.
METHODS: This qualitative research study examined POC testing across major diseases in Cape Town, Durban and Eastern Cape. We conducted 101 semi-structured interviews and seven focus group discussions with doctors, nurses, community health workers, patients, laboratory technicians, policymakers, hospital managers and diagnostic manufacturers.
RESULTS: In South Africa, diagnostics are characterised by a centralised system. Most tests conducted on the spot can be made to work successfully as POC tests. The majority of public/private clinics and smaller hospitals send samples via couriers to centralised laboratories and retrieve results the same way, via internet, fax or phone. The main challenge to POC testing lies in transporting samples and results, while delays risk patient loss from diagnostic/treatment pathways. Strategies to deal with associated delays create new problems, such as artificially prolonged turnaround times, strains on human resources and quality of testing, compounding additional diagnostic and treatment delays.
CONCLUSIONS: For POC testing to succeed, particular characteristics of diagnostic ecosystems and adaptations of professional practices to overcome associated challenges must be taken into account.
© 2014 John Wiley & Sons Ltd.

Entities:  

Keywords:  Afrique du Sud; South Africa; Sudáfrica; cualitativo; diagnostic delay; point-of-care testing; pruebas de diagnóstico inmediato; qualitatif; qualitative; retard de diagnostic; retraso diagnóstico; tests sur le lieu des soins

Mesh:

Year:  2015        PMID: 25496070     DOI: 10.1111/tmi.12450

Source DB:  PubMed          Journal:  Trop Med Int Health        ISSN: 1360-2276            Impact factor:   2.622


  19 in total

Review 1.  The potential of paper-based diagnostics to meet the ASSURED criteria.

Authors:  Suzanne Smith; Jan G Korvink; Dario Mager; Kevin Land
Journal:  RSC Adv       Date:  2018-10-03       Impact factor: 4.036

Review 2.  Rapid molecular tests for tuberculosis and tuberculosis drug resistance: a qualitative evidence synthesis of recipient and provider views.

Authors:  Nora Engel; Eleanor A Ochodo; Perpetua Wanjiku Karanja; Bey-Marrié Schmidt; Ricky Janssen; Karen R Steingart; Sandy Oliver
Journal:  Cochrane Database Syst Rev       Date:  2022-04-26

3.  Urine lipoarabinomannan for rapid tuberculosis diagnosis in HIV-infected adult outpatients in Khayelitsha.

Authors:  Bianca Sossen; Amanda Ryan; Joanna Bielawski; Riana Greyling; Gillian Matthews; Sheetal Hurribunce-James; René Goliath; Judy Caldwell; Graeme Meintjes
Journal:  South Afr J HIV Med       Date:  2021-04-26       Impact factor: 2.744

4.  Barriers to Point-of-Care Testing in India: Results from Qualitative Research across Different Settings, Users and Major Diseases.

Authors:  Nora Engel; Gayatri Ganesh; Mamata Patil; Vijayashree Yellappa; Nitika Pant Pai; Caroline Vadnais; Madhukar Pai
Journal:  PLoS One       Date:  2015-08-14       Impact factor: 3.240

5.  "I Do Feel Like a Scientist at Times": A Qualitative Study of the Acceptability of Molecular Point-Of-Care Testing for Chlamydia and Gonorrhoea to Primary Care Professionals in a Remote High STI Burden Setting.

Authors:  Lisa Natoli; Rebecca J Guy; Mark Shephard; Louise Causer; Steven G Badman; Belinda Hengel; Annie Tangey; James Ward; Tony Coburn; David Anderson; John Kaldor; Lisa Maher
Journal:  PLoS One       Date:  2015-12-29       Impact factor: 3.240

6.  Mycobacterial genomic DNA from used Xpert MTB/RIF cartridges can be utilised for accurate second-line genotypic drug susceptibility testing and spoligotyping.

Authors:  Rouxjeane Venter; Brigitta Derendinger; Margaretha de Vos; Samantha Pillay; Tanya Dolby; John Simpson; Natasha Kitchin; Ashley Ruiters; Paul D van Helden; Robin M Warren; Grant Theron
Journal:  Sci Rep       Date:  2017-11-01       Impact factor: 4.379

7.  Implementation of the Xpert MTB/RIF assay for tuberculosis in Mongolia: a qualitative exploration of barriers and enablers.

Authors:  Nicole L Rendell; Solongo Bekhbat; Gantungalag Ganbaatar; Munkhjargal Dorjravdan; Madhukar Pai; Claudia C Dobler
Journal:  PeerJ       Date:  2017-07-14       Impact factor: 2.984

8.  Making HIV testing work at the point of care in South Africa: a qualitative study of diagnostic practices.

Authors:  Nora Engel; Malika Davids; Nadine Blankvoort; Keertan Dheda; Nitika Pant Pai; Madhukar Pai
Journal:  BMC Health Serv Res       Date:  2017-06-17       Impact factor: 2.655

9.  Implementation of Point-of-Care Diagnostics in Rural Primary Healthcare Clinics in South Africa: Perspectives of Key Stakeholders.

Authors:  Tivani P Mashamba-Thompson; Ngcwalisa A Jama; Benn Sartorius; Paul K Drain; Rowan M Thompson
Journal:  Diagnostics (Basel)       Date:  2017-01-08

10.  A Survey on Use of Rapid Tests and Tuberculosis Diagnostic Practices by Primary Health Care Providers in South Africa: Implications for the Development of New Point-of-Care Tests.

Authors:  Malika Davids; Keertan Dheda; Nitika Pant Pai; Dolphina Cogill; Madhukar Pai; Nora Engel
Journal:  PLoS One       Date:  2015-10-28       Impact factor: 3.240

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.