Literature DB >> 25493923

A fluorescent probe for detection of an intracellular prognostic indicator in early-stage cancer.

Haiwei Ji1, Yijia Guan, Li Wu, Jinsong Ren, Daisuke Miyoshi, Naoki Sugimoto, Xiaogang Qu.   

Abstract

Cyclin A2 is a promising cancer prognostic indicator, but its intracellular in situ imaging is still a challenging task. This work designs an "off-on" fluorescent probe, which can fluorescently detect intracellular cyclin A2 and distinguish cancer cells. In addition, this work sheds light on the development of future protein biosensors.

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Year:  2015        PMID: 25493923     DOI: 10.1039/c4cc08789e

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  1 in total

1.  An aptamer-based four-color fluorometic method for simultaneous determination and imaging of alpha-fetoprotein, vascular endothelial growth factor-165, carcinoembryonic antigen and human epidermal growth factor receptor 2 in living cells.

Authors:  Jiayao Xu; Wenting Chen; Ming Shi; Yong Huang; Lina Fang; Shulin Zhao; Lifang Yao; Hong Liang
Journal:  Mikrochim Acta       Date:  2019-02-22       Impact factor: 5.833

  1 in total

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