| Literature DB >> 25491873 |
Qing Qing Dou1, Hong Chen Guo1, Enyi Ye2.
Abstract
Upconversion nanoparticles (UCNs) attract intensive attentions in biomedical applications. They have shown great potential in bioimaging, biomolecule detection, drug delivery, photodynamic therapy and cellular molecules interactions. Due to the anti-Stokes optical property and NIR excitation, UCNs overcome the drawbacks encountered in conventional luminescent biomarkers. High signal to noise ratio, low cytotoxicity and stable high throughput results are obtained using UCNs as luminescent labels or light triggers in biomedical applications. In this review article, the reason for choosing UCNs as biomedical agents, the progress of the UCNs development and case studies of their biomedical applications will be discussed.Entities:
Keywords: Multi-modality; NIR upconversion; Photo activation; Photodynamic therapy
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Year: 2014 PMID: 25491873 DOI: 10.1016/j.msec.2014.03.056
Source DB: PubMed Journal: Mater Sci Eng C Mater Biol Appl ISSN: 0928-4931 Impact factor: 7.328