Neil Ryan1, Graham Walkden2, Darko Lazic3, Paul Tierney1. 1. United Bristol Healthcare NHS Trust, ENT Bristol, United Kingdom. 2. North Bristol NHS Trust, Surgery Bristol, United Kingdom. 3. Great Western Hospital, Histopathology Swindon, United Kingdom.
Abstract
BACKGROUND: Collision tumors of the thyroid are a rare pathology that present a diagnostic and treatment challenge. In this report, we present an interesting case and a review of the current literature as to inform management. METHODS AND RESULTS: An 88-year-old woman presented with acute airway compromise and vocal cord paralysis. CT identified a thyroid mass and widespread metastasis. Histopathology identified the lesion as a collision tumor consisting of a squamous cell carcinoma (SCC) and papillary thyroid carcinoma. The patient was managed with surgery and palliative radiotherapy. However, she died from complications of a lower respiratory tract infection. We also present a review of the literature with 33 cases reviewed. CONCLUSION: Management of collision tumors is complex because of the duality of the pathology. They should be managed in a multidisciplinary team setting and treatment should be patient specific. Generally, the most aggressive neoplasm should guide treatment. We recommend surgical management with adjunct therapy.
BACKGROUND: Collision tumors of the thyroid are a rare pathology that present a diagnostic and treatment challenge. In this report, we present an interesting case and a review of the current literature as to inform management. METHODS AND RESULTS: An 88-year-old woman presented with acute airway compromise and vocal cord paralysis. CT identified a thyroid mass and widespread metastasis. Histopathology identified the lesion as a collision tumor consisting of a squamous cell carcinoma (SCC) and papillary thyroid carcinoma. The patient was managed with surgery and palliative radiotherapy. However, she died from complications of a lower respiratory tract infection. We also present a review of the literature with 33 cases reviewed. CONCLUSION: Management of collision tumors is complex because of the duality of the pathology. They should be managed in a multidisciplinary team setting and treatment should be patient specific. Generally, the most aggressive neoplasm should guide treatment. We recommend surgical management with adjunct therapy.
Authors: Nikolaos G Katsoulas; Konstantinos I Tosios; Hannah Afwerke Lynch; Rachel Uppgaard; Ioannis G Koutlas Journal: Head Neck Pathol Date: 2021-09-01
Authors: Ari M Abdullah; Aras J Qaradakhy; Mohsin M Ahmed; Abdulwahid M Salih; Sami S Omar; Fahmi H Kakamad; Hawbash M Rahim; Berwn A Abdulla; Shvan H Mohammed; Shaho F Ahmed; Hiwa O Baba; Rivan Hermiz Ishaac Journal: Ann Med Surg (Lond) Date: 2022-03-03