| Literature DB >> 25491158 |
Joanna Zeidler1, Dagmara Baraniak1, Tomasz Ostrowski2.
Abstract
This review summarizes briefly literature reports on nucleoside analogues containing five-membered aglycones based on imidazole-4-carboxamide, 1,2,4-triazole-3-carboxamide or 1,2,3-triazole-4-carboxamide structural motifs, which exhibit diverse therapeutically useful or promising biological properties. We do not describe synthetic approaches but try to present the essential activities of compounds and their established or postulated mechanisms of action.Entities:
Keywords: 1,2,3-Triazole nucleosides; 1,2,4-Triazole nucleosides; Imidazole nucleosides; Mechanism of action; Ribavirin
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Year: 2014 PMID: 25491158 DOI: 10.1016/j.ejmech.2014.11.057
Source DB: PubMed Journal: Eur J Med Chem ISSN: 0223-5234 Impact factor: 6.514