Literature DB >> 25491158

Bioactive nucleoside analogues possessing selected five-membered azaheterocyclic bases.

Joanna Zeidler1, Dagmara Baraniak1, Tomasz Ostrowski2.   

Abstract

This review summarizes briefly literature reports on nucleoside analogues containing five-membered aglycones based on imidazole-4-carboxamide, 1,2,4-triazole-3-carboxamide or 1,2,3-triazole-4-carboxamide structural motifs, which exhibit diverse therapeutically useful or promising biological properties. We do not describe synthetic approaches but try to present the essential activities of compounds and their established or postulated mechanisms of action.
Copyright © 2014 Elsevier Masson SAS. All rights reserved.

Entities:  

Keywords:  1,2,3-Triazole nucleosides; 1,2,4-Triazole nucleosides; Imidazole nucleosides; Mechanism of action; Ribavirin

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Substances:

Year:  2014        PMID: 25491158     DOI: 10.1016/j.ejmech.2014.11.057

Source DB:  PubMed          Journal:  Eur J Med Chem        ISSN: 0223-5234            Impact factor:   6.514


  2 in total

1.  Antiviral activity of 1,2,4-triazole derivatives (microreview).

Authors:  Nataliia V Simurova; Olena I Maiboroda
Journal:  Chem Heterocycl Compd (N Y)       Date:  2021-05-14       Impact factor: 1.277

Review 2.  Recent Progress in Nitro-Promoted Direct Functionalization of Pyridones and Quinolones.

Authors:  Feiyue Hao; Nagatoshi Nishiwaki
Journal:  Molecules       Date:  2020-02-05       Impact factor: 4.411

  2 in total

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