Literature DB >> 25490361

[Efficacy of Venarus in treatment of patients with post-thrombotic disease of lower limbs].

I N Son'kin, E V Shaĭdakov, D V Krylov, V L Bulatov, A S Remizov, M V Rezvantsev.   

Abstract

The authors studied efficacy of Venarus in comprehensive treatment of patients presenting with post-thrombotic disease. An open multicenter retrospective study included a total of 110 patients subdivided into two groups. Group One (Study Group) consisted of 51 patients with post-thrombotic syndrome, undergoing comprehensive medical treatment with the use of phlebotonic agent Venarus. Group Two (Control Group) comprised 59 patients with post-thrombotic syndrome undergoing similar conservative treatment but without taking phlebotonics. It was proved that Venarus included into comprehensive treatment of patients with post-thrombotic syndrome led to a statistically significant increase of both psychological and social activity and improved patients' quality of life. During the standard term of administration (2 months) Venarus levelled subjective symptoms and certain objective symptoms (according to the Villalta Scale) of post-thrombotic syndrome. After 2-month use Venarus demonstrated the highest efficacy in treating patients with mild-to-moderate post-thrombotic syndrome. The maximal efficacy was observed after 3 months of administration in standard doses. No side effects were noted during the whole period of the study.

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Year:  2014        PMID: 25490361

Source DB:  PubMed          Journal:  Angiol Sosud Khir        ISSN: 1027-6661


  1 in total

Review 1.  Micronized purified flavonoid fraction for the treatment of chronic venous insufficiency, with a focus on postthrombotic syndrome: A narrative review.

Authors:  Ke Xuan Li; Gisele Diendéré; Jean-Philippe Galanaud; Nada Mahjoub; Susan R Kahn
Journal:  Res Pract Thromb Haemost       Date:  2021-05-08
  1 in total

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