Robert L Avery1, Sophie J Bakri, Mark S Blumenkranz, Alexander J Brucker, Emmett T Cunningham, Donald J DʼAmico, Pravin U Dugel, Harry W Flynn, K Bailey Freund, Julia A Haller, J Michael Jumper, Jeffrey M Liebmann, Colin A McCannel, William F Mieler, Christopher N Ta, George A Williams. 1. *California Retina Consultants and Research Foundation, Santa Barbara, California; †Mayo Clinic, Rochester, Minnesota; ‡Byers Eye Institute, Stanford University School of Medicine, Stanford, California; §Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania; ¶California Pacific Medical Center, San Francisco, California; **The Francis I. Proctor Foundation, UCSF School of Medicine, San Francisco, California; ††West Coast Retina, San Francisco, California; ‡‡Weill Cornell Medical College, New York-Presbyterian Medical Center, New York, New York; §§Keck School of Medicine, University of Southern California, Los Angeles, California; ¶¶Bascom Palmer Eye Institute, University of Miami, Miami, Florida; ***Vitreous-Retina-Macula Consultants of New York, New York; †††Wills Eye Hospital, Philadelphia, Pennsylvania; ‡‡‡Manhattan Eye, Ear & Throat Hospital, New York University Medical Center, New York, New York; §§§Jules Stein Eye Institute, University of California, Los Angeles, California; ¶¶¶University of Illinois, Chicago, Illinois; ****Stanford University School of Medicine, Stanford, California; and ††††Oakland University William Beaumont School of Medicine, Beaumont Eye Institute, Royal Oak, Michigan.
Abstract
PURPOSE: To review evidence and provide updated guidelines on intravitreal (IVT) injection technique and monitoring. METHODS: A review of the published literature on IVT injection from 2004 to 2014 formed the basis for round table deliberations by an expert panel of ophthalmologists. RESULTS: The dramatic increase in the number of IVT injections has been accompanied by a comparable increase in evidence surrounding IVT practice patterns and techniques. The expert panel identified a number of areas that have evolved since publication of the original IVT injection guidelines in 2004, the most notable of which were a lack of evidence to support the routine use of pre-, peri-, and postinjection antibiotics to reduce the risk of endophthalmitis, and the role of aerosolized droplets containing oral contaminants from the patient and/or providers as a potential source of infection. The panel emphasized the continued importance of applying povidone-iodine to and avoiding eyelid contact with the intended injection site and needle. CONCLUSION: Updated guidelines on IVT injection technique and monitoring are proposed based on a review of published literature and expert panel deliberations.
PURPOSE: To review evidence and provide updated guidelines on intravitreal (IVT) injection technique and monitoring. METHODS: A review of the published literature on IVT injection from 2004 to 2014 formed the basis for round table deliberations by an expert panel of ophthalmologists. RESULTS: The dramatic increase in the number of IVT injections has been accompanied by a comparable increase in evidence surrounding IVT practice patterns and techniques. The expert panel identified a number of areas that have evolved since publication of the original IVT injection guidelines in 2004, the most notable of which were a lack of evidence to support the routine use of pre-, peri-, and postinjection antibiotics to reduce the risk of endophthalmitis, and the role of aerosolized droplets containing oral contaminants from the patient and/or providers as a potential source of infection. The panel emphasized the continued importance of applying povidone-iodine to and avoiding eyelid contact with the intended injection site and needle. CONCLUSION: Updated guidelines on IVT injection technique and monitoring are proposed based on a review of published literature and expert panel deliberations.
Authors: Kathleen A Regan; Justin L Gottlieb; Michael M Altaweel; Mihai Mititelu; Barbara A Blodi; T Michael Nork; Kimberly E Stepien; Jonathan S Chang Journal: Ophthalmol Retina Date: 2020-08
Authors: Cecilia S Lee; Bryan Hong; Sundeep K Kasi; Christopher Aderman; Katherine E Talcott; Murtaza K Adam; Bryan Yue; Lakshmi Akileswaran; Kenji Nakamichi; Yue Wu; Kasra A Rezaei; Lisa C Olmos de Koo; Yewlin E Chee; Aaron Y Lee; Sunir J Garg; Russell N Van Gelder Journal: Am J Ophthalmol Date: 2020-03-23 Impact factor: 5.258