Zülfükar Yılmaz1, Yaşar Yıldırım2, Fatma Yılmaz Aydın3, Emre Aydın3, Ali Kemal Kadiroğlu2, Mehmet Emin Yılmaz2, Halit Acet4. 1. Department of Nephrology, Faculty of Medicine, Dicle University, Diyarbakır, Turkey. Electronic address: drzulf21@gmail.com. 2. Department of Nephrology, Faculty of Medicine, Dicle University, Diyarbakır, Turkey. 3. Department of Internal Medicine, Faculty of Medicine, Dicle University, Diyarbakır, Turkey. 4. Department of Cardiology, Faculty of Medicine, Dicle University, Diyarbakır, Turkey.
Abstract
BACKGROUND AND OBJECTIVE: Fluid overload is a common and serious problem that leads to severe complications in dialysis patients. We aimed to compare hydration status as measured with bioimpedance analysis (BIA) method in hemodialysis (HD) and peritoneal dialysis (PD) patients, as well as investigating the association between blood pressure, left ventricular mass index (LVMI) and hydration status. MATERIALS AND METHODS: We examined 43 HD and 33 PD patients. Blood pressure was recorded. In each group, echocardiographic examinations were performed on all patients. Hydration status was assessed using multifrequency bioelectrical impedance analysis. Overhydration was defined as an overhydration (OH)/extracellular water (ECW) ratio of >0.15. RESULTS: The OH/ECW ratio was significantly higher in PD patients compared to post-HD patients. Overhydration was statistically more frequent in PD than in post-HD patients (30.3% vs. 11.6%, P=0.043). Systolic blood pressure (SBP) in both post-HD and PD groups, and LVMI in the PD group were found to be significantly higher in overhydrated patients than non-overhydrated patients. In multiple linear regression analyses, increased OH/ECW ratio was independently associated with higher SBP and LVMI. CONCLUSIONS: Fluid overload may be an even more prevalent and serious problem in PD patients. Overhydration is closely associated with increased blood pressure and LVMI. OH/ECW ratio, a derived parameter of fluid load measured by BIA, was a significant and independent determinant of SBP and LVMI.
BACKGROUND AND OBJECTIVE: Fluid overload is a common and serious problem that leads to severe complications in dialysis patients. We aimed to compare hydration status as measured with bioimpedance analysis (BIA) method in hemodialysis (HD) and peritoneal dialysis (PD) patients, as well as investigating the association between blood pressure, left ventricular mass index (LVMI) and hydration status. MATERIALS AND METHODS: We examined 43 HD and 33 PDpatients. Blood pressure was recorded. In each group, echocardiographic examinations were performed on all patients. Hydration status was assessed using multifrequency bioelectrical impedance analysis. Overhydration was defined as an overhydration (OH)/extracellular water (ECW) ratio of >0.15. RESULTS: The OH/ECW ratio was significantly higher in PDpatients compared to post-HDpatients. Overhydration was statistically more frequent in PD than in post-HDpatients (30.3% vs. 11.6%, P=0.043). Systolic blood pressure (SBP) in both post-HD and PD groups, and LVMI in the PD group were found to be significantly higher in overhydrated patients than non-overhydrated patients. In multiple linear regression analyses, increased OH/ECW ratio was independently associated with higher SBP and LVMI. CONCLUSIONS: Fluid overload may be an even more prevalent and serious problem in PDpatients. Overhydration is closely associated with increased blood pressure and LVMI. OH/ECW ratio, a derived parameter of fluid load measured by BIA, was a significant and independent determinant of SBP and LVMI.
Authors: Elisabeth Schwaiger; Amrei Simon; Peter Wabel; Benjamin Schairer; Carolin Berner; Lorenzo Signorini; Matthäus Ernstbrunner; Rayko Evstatiev; Philipp Schwabl; Georg Hinterholzer; Florian Frommlet; Andreas Vychytil; Christian J Müller; Manfred Hecking Journal: Sci Rep Date: 2020-02-18 Impact factor: 4.379
Authors: Man Ching Law; Bonnie Ching-Ha Kwan; Janny Suk-Fun Fung; Kai Ming Chow; Jack K C Ng; Wing-Fai Pang; Phyllis Mei-Shan Cheng; Chi Bon Leung; Cheuk Chun Szeto Journal: BMC Nephrol Date: 2019-12-09 Impact factor: 2.388