| Literature DB >> 25487806 |
Shizuo Kayama1, Norifumi Shigemoto2, Ryuichi Kuwahara3, Kenshiro Oshima4, Hideki Hirakawa5, Junzo Hisatsune1, Thomas Jové6, Hisaaki Nishio7, Katsutoshi Yamasaki8, Yasunao Wada9, Takeshi Ueshimo10, Tetsuya Miura10, Taijiro Sueda11, Makoto Onodera12, Michiya Yokozaki12, Masahira Hattori4, Hiroki Ohge13, Motoyuki Sugai14.
Abstract
We have determined the DNA sequence of Klebsiella pneumoniae multidrug resistance plasmid pKPI-6, which is a self-transmissible IncN-type plasmid. pKPI-6 harboring blaIMP-6 and blaCTX-M-2 confers a stealth-type carbapenem resistance phenotype on members of the family Enterobacteriaceae that is not detectable with imipenem. pKPI-6 is already epidemic in Japan, favoring the dissemination of IMP-6 and CTX-M-2 in members of the family Enterobacteriaceae.Entities:
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Year: 2014 PMID: 25487806 PMCID: PMC4335907 DOI: 10.1128/AAC.04759-14
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191