| Literature DB >> 25487637 |
Ana R Fusco da Costa1, Tarcisio Fedrizzi2, Maria L Lopes1, Monica Pecorari3, Wana L Oliveira da Costa1, Elisabetta Giacobazzi2, Jeann R da Costa Bahia1, Veronica De Sanctis2, Karla V Batista Lima1, Roberto Bertorelli2, Antonella Grottola3, Anna Fabio3, Alessandro Mariottini4, Pamela Ferretti2, Francesca Di Leva2, Giulia Fregni Serpini3, Sara Tagliazucchi3, Fabio Rumpianesi3, Olivier Jousson2, Nicola Segata2, Enrico Tortoli5.
Abstract
Fourteen mycobacterial strains isolated from pulmonary samples of independent patients in the state of Pará (Brazil), and three strains isolated in Italy, were characterized using a polyphasic approach. Thorough genetic investigation, including whole-genome sequencing, demonstrated that the strains belong to the M. simiae complex, being most closely related to Mycobacterium interjectum. For 14 of the strains, evidence emerged supporting their inclusion in a previously unreported species of the genus Mycobacterium, for which the name Mycobacterium paraense sp. nov. is proposed (type strain, IEC26(T) = DSM 46749(T) = CCUG 66121(T)). The novel species is characterized by slow growth, unpigmented or pale yellow scotochromogenic colonies, and a HPLC mycolic acid profile different from other known mycobacteria. In different genetic regions, high sequence microheterogeneity was detected.Entities:
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Year: 2014 PMID： 25487637 DOI： 10.1099/ijs.0.068395-0
Source DB: PubMed Journal: Int J Syst Evol Microbiol ISSN： 1466-5026 Impact factor: 2.747