Tara S Peris1, Scott N Compton2, Philip C Kendall3, Boris Birmaher4, Joel Sherrill5, John March6, Elizabeth Gosch7, Golda Ginsburg8, Moira Rynn9, James T McCracken10, Courtney P Keeton8, Dara Sakolsky4, Cynthia Suveg11, Sasha Aschenbrand9, Daniel Almirall12, Satish Iyengar4, John T Walkup13, Anne Marie Albano9, John Piacentini10. 1. Semel Institute for Neuroscience and Human Behavior University of California, Los Angeles. 2. Department of Psychology and Behavioral Sciences, Duke University Medical Center. 3. Department of Psychology, Temple University. 4. Western Psychiatric Institute and Clinic-University of Pittsburgh Medical Center. 5. Division of Services and Intervention Research, National Institute of Mental Health. 6. Department of Psychiatry and Behavioral Sciences, Duke University Medical Center. 7. Department of Psychology, Philadelphia College of Osteopathic Medicine. 8. Division of Child and Adolescent Psychiatry, Johns Hopkins Medical Institutions. 9. New York State Psychiatric Institute-Columbia University Medical Center. 10. Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles. 11. Department of Psychology, University of Georgia. 12. Institute for Social Research, University of Michigan. 13. Division of Child and Adolescent Psychiatry, Weill Cornell Medical College.
Abstract
OBJECTIVE: To evaluate changes in the trajectory of youth anxiety following the introduction of specific cognitive-behavior therapy (CBT) components: relaxation training, cognitive restructuring, and exposure tasks. METHOD: Four hundred eighty-eight youths ages 7-17 years (50% female; 74% ≤ 12 years) were randomly assigned to receive either CBT, sertraline (SRT), their combination (COMB), or pill placebo (PBO) as part of their participation in the Child/Adolescent Anxiety Multimodal Study (CAMS). Youths in the CBT conditions were evaluated weekly by therapists using the Clinical Global Impression Scale-Severity (CGI-S; Guy, 1976) and the Children's Global Assessment Scale (CGAS; Shaffer et al., 1983) and every 4 weeks by blind independent evaluators (IEs) using the Pediatric Anxiety Ratings Scale (PARS; RUPP Anxiety Study Group, 2002). Youths in SRT and PBO were included as controls. RESULTS: Longitudinal discontinuity analyses indicated that the introduction of both cognitive restructuring (e.g., changing self-talk) and exposure tasks significantly accelerated the rate of progress on measures of symptom severity and global functioning moving forward in treatment; the introduction of relaxation training had limited impact. Counter to expectations, no strategy altered the rate of progress in the specific domain of anxiety that it was intended to target (i.e., somatic symptoms, anxious self-talk, avoidance behavior). CONCLUSIONS: Findings support CBT theory and suggest that cognitive restructuring and exposure tasks each make substantial contributions to improvement in youth anxiety. Implications for future research are discussed. (PsycINFO Database Record (c) 2015 APA, all rights reserved).
RCT Entities:
OBJECTIVE: To evaluate changes in the trajectory of youth anxiety following the introduction of specific cognitive-behavior therapy (CBT) components: relaxation training, cognitive restructuring, and exposure tasks. METHOD: Four hundred eighty-eight youths ages 7-17 years (50% female; 74% ≤ 12 years) were randomly assigned to receive either CBT, sertraline (SRT), their combination (COMB), or pill placebo (PBO) as part of their participation in the Child/Adolescent Anxiety Multimodal Study (CAMS). Youths in the CBT conditions were evaluated weekly by therapists using the Clinical Global Impression Scale-Severity (CGI-S; Guy, 1976) and the Children's Global Assessment Scale (CGAS; Shaffer et al., 1983) and every 4 weeks by blind independent evaluators (IEs) using the Pediatric Anxiety Ratings Scale (PARS; RUPP Anxiety Study Group, 2002). Youths in SRT and PBO were included as controls. RESULTS: Longitudinal discontinuity analyses indicated that the introduction of both cognitive restructuring (e.g., changing self-talk) and exposure tasks significantly accelerated the rate of progress on measures of symptom severity and global functioning moving forward in treatment; the introduction of relaxation training had limited impact. Counter to expectations, no strategy altered the rate of progress in the specific domain of anxiety that it was intended to target (i.e., somatic symptoms, anxious self-talk, avoidance behavior). CONCLUSIONS: Findings support CBT theory and suggest that cognitive restructuring and exposure tasks each make substantial contributions to improvement in youth anxiety. Implications for future research are discussed. (PsycINFO Database Record (c) 2015 APA, all rights reserved).
Authors: Philip C Kendall; Scott N Compton; John T Walkup; Boris Birmaher; Anne Marie Albano; Joel Sherrill; Golda Ginsburg; Moira Rynn; James McCracken; Elizabeth Gosch; Courtney Keeton; Lindsey Bergman; Dara Sakolsky; Cindy Suveg; Satish Iyengar; John March; John Piacentini Journal: J Anxiety Disord Date: 2010-02-06
Authors: Andrew T Drysdale; Catherine A Hartley; Siobhan S Pattwell; Erika J Ruberry; Leah H Somerville; Scott N Compton; Francis S Lee; B J Casey; John T Walkup Journal: Biol Psychiatry Date: 2013-09-25 Impact factor: 13.382
Authors: John March; Susan Silva; Stephen Petrycki; John Curry; Karen Wells; John Fairbank; Barbara Burns; Marisa Domino; Steven McNulty; Benedetto Vitiello; Joanne Severe Journal: JAMA Date: 2004-08-18 Impact factor: 56.272
Authors: Scott N Compton; John T Walkup; Anne Marie Albano; John C Piacentini; Boris Birmaher; Joel T Sherrill; Golda S Ginsburg; Moira A Rynn; James T McCracken; Bruce D Waslick; Satish Iyengar; Phillip C Kendall; John S March Journal: Child Adolesc Psychiatry Ment Health Date: 2010-01-05 Impact factor: 3.033
Authors: Emily M Becker-Haimes; Kelsie H Okamura; Courtney Benjamin Wolk; Ronnie Rubin; Arthur C Evans; Rinad S Beidas Journal: J Anxiety Disord Date: 2017-04-27
Authors: Adele M Hayes; Carly Yasinski; Damion Grasso; C Beth Ready; Elizabeth Alpert; Thomas McCauley; Charles Webb; Esther Deblinger Journal: Behav Ther Date: 2016-06-25
Authors: Robert R Selles; Martin Franklin; Jeffrey Sapyta; Scott N Compton; Doug Tommet; Richard N Jones; Abbe Garcia; Jennifer Freeman Journal: Child Psychiatry Hum Dev Date: 2018-04
Authors: Jerome H Taylor; Angeli Landeros-Weisenberger; Catherine Coughlin; Jilian Mulqueen; Jessica A Johnson; Daniel Gabriel; Margot O Reed; Ewgeni Jakubovski; Michael H Bloch Journal: Neuropsychopharmacology Date: 2017-08-29 Impact factor: 7.853