Literature DB >> 2548536

Urinary neopterin concentrations in rhesus monkeys after infection with simian immunodeficiency virus (SIVmac 251).

C Fendrich1, W Lüke, C Stahl-Hennig, O Herchenröder, D Fuchs, H Wachter, G Hunsmann.   

Abstract

Two rhesus monkeys were infected with SIVmac 251. Elevated urinary neopterin concentrations were observed as the first sign of infection. Virus-specific antibodies were detected 14 days after infection, when neopterin concentrations were already decreasing. The neopterin levels of one animal remained elevated and the virus was repeatedly isolated. Urinary or serum neopterin concentrations appear to be early markers for SIV infection and viremia in rhesus monkeys.

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Year:  1989        PMID: 2548536     DOI: 10.1097/00002030-198905000-00010

Source DB:  PubMed          Journal:  AIDS        ISSN: 0269-9370            Impact factor:   4.177


  13 in total

1.  Construction, replication, and immunogenic properties of a simian immunodeficiency virus expressing interleukin-2.

Authors:  B R Gundlach; H Linhart; U Dittmer; S Sopper; S Reiprich; D Fuchs; B Fleckenstein; G Hunsmann; C Stahl-Hennig; K Uberla
Journal:  J Virol       Date:  1997-03       Impact factor: 5.103

2.  Value of urinary neopterin in the differential diagnosis of bacterial and viral infections.

Authors:  H Denz; D Fuchs; A Hausen; H Huber; D Nachbaur; G Reibnegger; J Thaler; E R Werner; H Wachter
Journal:  Klin Wochenschr       Date:  1990-02-15

3.  The Use of Neopterin as a Noninvasive Marker in Monitoring Diseases in Wild Chimpanzees.

Authors:  Therese Löhrich; Verena Behringer; Roman M Wittig; Tobias Deschner; Fabian H Leendertz
Journal:  Ecohealth       Date:  2018-08-16       Impact factor: 3.184

4.  Simian immunodeficiency virus containing mutations in N-terminal tyrosine residues and in the PxxP motif in Nef replicates efficiently in rhesus macaques.

Authors:  S Carl; A J Iafrate; S M Lang; N Stolte; C Stahl-Hennig; K Mätz-Rensing; D Fuchs; J Skowronski; F Kirchhoff
Journal:  J Virol       Date:  2000-05       Impact factor: 5.103

5.  The human immunodeficiency virus type 1 nef gene can to a large extent replace simian immunodeficiency virus nef in vivo.

Authors:  F Kirchhoff; J Münch; S Carl; N Stolte; K Mätz-Rensing; D Fuchs; P T Haaft; J L Heeney; T Swigut; J Skowronski; C Stahl-Hennig
Journal:  J Virol       Date:  1999-10       Impact factor: 5.103

6.  Importance of vpr for infection of rhesus monkeys with simian immunodeficiency virus.

Authors:  S M Lang; M Weeger; C Stahl-Hennig; C Coulibaly; G Hunsmann; J Müller; H Müller-Hermelink; D Fuchs; H Wachter; M M Daniel
Journal:  J Virol       Date:  1993-02       Impact factor: 5.103

7.  Long-term tolerance and efficacy of 3'-azidothymidine and 3'-fluorothymidine treatment of asymptomatic monkeys infected with simian immunodeficiency virus.

Authors:  D Böttiger; L Ståhle; S L Li; B Oberg
Journal:  Antimicrob Agents Chemother       Date:  1992-08       Impact factor: 5.191

8.  Age, but not anthelmintic treatment, is associated with urinary neopterin levels in semi-free ranging Barbary macaques.

Authors:  Nadine Müller; Michael Heistermann; Christina Strube; Oliver Schülke; Julia Ostner
Journal:  Sci Rep       Date:  2017-02-03       Impact factor: 4.379

9.  Validation of a Method for the Assessment of Urinary Neopterin Levels to Monitor Health Status in Non-human-primate Species.

Authors:  Verena Behringer; Jeroen M G Stevens; Fabian H Leendertz; Gottfried Hohmann; Tobias Deschner
Journal:  Front Physiol       Date:  2017-02-06       Impact factor: 4.566

10.  Species-specific host factors rather than virus-intrinsic virulence determine primate lentiviral pathogenicity.

Authors:  Simone Joas; Erica H Parrish; Clement W Gnanadurai; Edina Lump; Christina M Stürzel; Nicholas F Parrish; Gerald H Learn; Ulrike Sauermann; Berit Neumann; Kerstin Mätz Rensing; Dietmar Fuchs; James M Billingsley; Steven E Bosinger; Guido Silvestri; Cristian Apetrei; Nicolas Huot; Thalia Garcia-Tellez; Michaela Müller-Trutwin; Dominik Hotter; Daniel Sauter; Christiane Stahl-Hennig; Beatrice H Hahn; Frank Kirchhoff
Journal:  Nat Commun       Date:  2018-04-10       Impact factor: 14.919

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