Literature DB >> 25484134

Beneficial impact of multidisciplinary team management on the survival in different stages of oral cavity cancer patients: results of a nationwide cohort study in Taiwan.

Wen-Chen Tsai1, Pei-Tseng Kung2, Shih-Ting Wang1, Kuang-Hua Huang1, Shih-An Liu3.   

Abstract

OBJECTIVES: The aim of this study was to investigate the association between multidisciplinary team (MDT) management and survival of oral cavity cancer patients using a nationwide database in Taiwan.
MATERIALS AND METHODS: A nationwide cohort study was conducted between 2005 and 2008. The follow-up end point was 2010. Claims data of oral cavity cancer patients were retrieved from the Taiwan Cancer Registry Database. Secondary data were obtained from the Taiwan's National Health Insurance Research Database. Among 19,766 newly diagnosed oral cavity cancer patients, we identified 16,991 patients who underwent treatment between 2004 and 2008 for further analyses.
RESULTS: Overall survival was compared between patients who received MDT management (n=3324) and those who did not (n=13,367). Hazard ratios (HR) of death in patients with MDT management were also analyzed. Patients with MDT management had a lower risk of death when compared with that of patients without MDT management (HR: 0.94, 95% confidence intervals (CI): 0.89-1.00; P=0.032). The effect of MDT management on survival was stronger for male patients than for female patients (HR: 0.94, 95% CI: 0.89-1.00; P=0.040 versus HR: 0.98, 95% CI: 0.75-1.27; P=0.866). In addition, the effect of MDT management was strong among patients with a Charlson Comorbidity Index between 4 and 6, in those without coexisting catastrophic illness/injury, and in patients with stage IV diseases.
CONCLUSION: Survival rates in oral cavity cancer patients with MDT management appeared to be marginally better than those of patients without MDT management.
Copyright © 2014 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Beneficial impact; Multidisciplinary team; Nationwide database; Oral cavity cancer; Propensity score; Survival analysis

Mesh:

Year:  2014        PMID: 25484134     DOI: 10.1016/j.oraloncology.2014.11.006

Source DB:  PubMed          Journal:  Oral Oncol        ISSN: 1368-8375            Impact factor:   5.337


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