Literature DB >> 25483680

Current opinion and review on peanut oral immunotherapy.

Sharon Deol1, J Andrew Bird.   

Abstract

In the last decade, peanut oral immunotherapy research has shown promise as an alternative treatment to avoidance in peanut-allergic patients. Research has not only focused on desensitization, but also on immunologic changes and sustained-tolerance. This article reviews the current literature and the historical background of oral immunotherapy as well as immune mechanisms in oral immunotherapy and other therapies being explored in food allergic individuals.

Entities:  

Keywords:  DC, dendritic cells; FAHF-2, food allergy herbal formula-2; OFC, oral food challenge; OIT, oral immunotherapy; SCIT, subcutaneous immunotherapy; TCM, traditional Chinese medicine; desensitization; food allergy; iTreg, induced Treg cells; oral immunotherapy; peanut; treatment

Mesh:

Substances:

Year:  2014        PMID: 25483680      PMCID: PMC5443074          DOI: 10.4161/hv.32190

Source DB:  PubMed          Journal:  Hum Vaccin Immunother        ISSN: 2164-5515            Impact factor:   3.452


  49 in total

1.  Successful oral desensitization for systemic peanut allergy.

Authors:  Lyndon Mansfield
Journal:  Ann Allergy Asthma Immunol       Date:  2006-08       Impact factor: 6.347

2.  Specific oral tolerance induction in children with very severe cow's milk-induced reactions.

Authors:  Giorgio Longo; Egidio Barbi; Irene Berti; Rosanna Meneghetti; Angela Pittalis; Luca Ronfani; Alessandro Ventura
Journal:  J Allergy Clin Immunol       Date:  2007-12-26       Impact factor: 10.793

3.  Rush oral immunotherapy in children with persistent cow's milk allergy.

Authors:  Ute Staden; Katharina Blumchen; Nike Blankenstein; Nicole Dannenberg; Helen Ulbricht; Kerstin Dobberstein; Mandy Ziegert; Bodo Niggemann; Ulrich Wahn; Kirsten Beyer
Journal:  J Allergy Clin Immunol       Date:  2008-07-07       Impact factor: 10.793

4.  A phase II, randomized, double‑blind, parallel‑group, placebo‑controlled oral food challenge trial of Xolair (omalizumab) in peanut allergy.

Authors:  Hugh A Sampson; Donald Y M Leung; A Wesley Burks; Gideon Lack; Sami L Bahna; Stacie M Jones; Dennis A Wong
Journal:  J Allergy Clin Immunol       Date:  2011-03-11       Impact factor: 10.793

5.  Peanut oral immunotherapy is not ready for clinical use.

Authors:  Ananth Thyagarajan; Pooja Varshney; Stacie M Jones; Scott Sicherer; Robert Wood; Brian P Vickery; Hugh Sampson; A Wesley Burks
Journal:  J Allergy Clin Immunol       Date:  2010-07       Impact factor: 10.793

6.  Evidence of pathway-specific basophil anergy induced by peanut oral immunotherapy in peanut-allergic children.

Authors:  A Thyagarajan; S M Jones; A Calatroni; L Pons; M Kulis; C S Woo; M Kamalakannan; B P Vickery; A M Scurlock; A Wesley Burks; W G Shreffler
Journal:  Clin Exp Allergy       Date:  2012-08       Impact factor: 5.018

7.  Efficacy and safety of high-dose peanut oral immunotherapy with factors predicting outcome.

Authors:  K Anagnostou; A Clark; Y King; S Islam; J Deighton; P Ewan
Journal:  Clin Exp Allergy       Date:  2011-03-18       Impact factor: 5.018

8.  Safety of a peanut oral immunotherapy protocol in children with peanut allergy.

Authors:  Alison M Hofmann; Amy M Scurlock; Stacie M Jones; Kricia P Palmer; Yuliya Lokhnygina; Pamela H Steele; Janet Kamilaris; A Wesley Burks
Journal:  J Allergy Clin Immunol       Date:  2009-05-27       Impact factor: 10.793

9.  Induction of tolerance after establishment of peanut allergy by the food allergy herbal formula-2 is associated with up-regulation of interferon-gamma.

Authors:  C Qu; K Srivastava; J Ko; T F Zhang; H A Sampson; X-M Li
Journal:  Clin Exp Allergy       Date:  2007-06       Impact factor: 5.018

10.  Intestinal CD103+, but not CX3CR1+, antigen sampling cells migrate in lymph and serve classical dendritic cell functions.

Authors:  Olga Schulz; Elin Jaensson; Emma K Persson; Xiaosun Liu; Tim Worbs; William W Agace; Oliver Pabst
Journal:  J Exp Med       Date:  2009-12-14       Impact factor: 14.307

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  1 in total

1.  Microneedles coated with peanut allergen enable desensitization of peanut sensitized mice.

Authors:  Akhilesh Kumar Shakya; Rohan S J Ingrole; Gaurav Joshi; Md Jasim Uddin; Sara Anvari; Carla M Davis; Harvinder Singh Gill
Journal:  J Control Release       Date:  2019-10-15       Impact factor: 9.776

  1 in total

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