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Literature DB >> 25483427

Well-defined biohybrids using reversible-deactivation radical polymerization procedures.

Saadyah Averick¹, Ryan A Mehl², Subha R Das³, Krzysztof Matyjaszewski⁴.

Abstract

The use of reversible deactivation radical polymerization (RDRP) methods has significantly expanded the field of bioconjugate synthesis. RDRP procedures have allowed the preparation of a broad range of functional materials that could not be realized using prior art poly(ethylene glycol) functionalization. The review of procedures for synthesis of biomaterials is presented with a special focus on the use of RDRP to prepare biohybrids with proteins, DNA and RNA.

Entities: Chemical

Keywords: ATRP; Bioconjugates; Biohybrids; Polymer; RAFT; RDRP

Mesh：

Substances：

Year: 2014 PMID： 25483427 DOI： 10.1016/j.jconrel.2014.11.030

Source DB: PubMed Journal: J Control Release ISSN： 0168-3659 Impact factor: 9.776

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Cited

10 in total

1. RGD-decorated cholesterol stabilized polyplexes for targeted siRNA delivery to glioblastoma cells.

Authors: Bo Lou; Kate Connor; Kieron Sweeney; Ian S Miller; Alice O'Farrell; Eduardo Ruiz-Hernandez; David M Murray; Garry P Duffy; Alan Wolfe; Enrico Mastrobattista; Annette T Byrne; Wim E Hennink
Journal: Drug Deliv Transl Res Date: 2019-06 Impact factor: 4.617

2. Polymer Structure and Conformation Alter the Antigenicity of Virus-like Particle-Polymer Conjugates.

Authors: Parker W Lee; Sergey A Isarov; Jaqueline D Wallat; Sudheer K Molugu; Sourabh Shukla; Jessie E P Sun; Jun Zhang; Yi Zheng; Melissa Lucius Dougherty; Dominik Konkolewicz; Phoebe L Stewart; Nicole F Steinmetz; Michael J A Hore; Jonathan K Pokorski
Journal: J Am Chem Soc Date: 2017-01-25 Impact factor: 15.419

Well-defined biohybrids using reversible-deactivation radical polymerization procedures.

1. RGD-decorated cholesterol stabilized polyplexes for targeted siRNA delivery to glioblastoma cells.

2. Polymer Structure and Conformation Alter the Antigenicity of Virus-like Particle-Polymer Conjugates.

3. Hydrolytically Stable Maleimide-End-Functionalized Polymers for Site-Specific Protein Conjugation.

4. Enhancing Conjugation Yield of Brush Polymer-Protein Conjugates by Increasing Linker Length at the Polymer End-Group.

5. Direct ATRP of Methacrylic Acid with Iron-Porphyrin Based Catalysts.

6. Bright Fluorescent Nanotags from Bottlebrush Polymers with DNA-Tipped Bristles.

7. A Heparin-Mimicking Block Copolymer Both Stabilizes and Increases the Activity of Fibroblast Growth Factor 2 (FGF2).

8. Self-Assembling Peptide Epitopes as Novel Platform for Anticancer Vaccination.

9. Automated prediction of site and sequence of protein modification with ATRP initiators.

10. Structure and Dynamics of Thermosensitive pDNA Polyplexes Studied by Time-Resolved Fluorescence Spectroscopy.