Literature DB >> 25483056

Opening the gate to DNA replication.

Alberto Riera1, Christian Speck.   

Abstract

Keywords:  DNA entry gate; DNA licensing; DNA replication; MCM2-7; pre-RC; replicative helicase

Mesh：

Substances：

Year:  2015        PMID： 25483056      PMCID： PMC4353067          DOI： 10.4161/15384101.2014.987624

Source DB:  PubMed          Journal:  Cell Cycle        ISSN： 1551-4005            Impact factor:   4.534


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  7 in total

1.  Differences in the single-stranded DNA binding activities of MCM2-7 and MCM467: MCM2 and MCM5 define a slow ATP-dependent step.

Authors:  Matthew L Bochman; Anthony Schwacha
Journal:  J Biol Chem       Date:  2007-09-25       Impact factor: 5.157

2.  An ORC/Cdc6/MCM2-7 complex is formed in a multistep reaction to serve as a platform for MCM double-hexamer assembly.

Authors:  Alejandra Fernández-Cid; Alberto Riera; Silvia Tognetti; M Carmen Herrera; Stefan Samel; Cecile Evrin; Christian Winkler; Emanuela Gardenal; Stefan Uhle; Christian Speck
Journal:  Mol Cell       Date:  2013-04-18       Impact factor: 17.970

3.  Concerted loading of Mcm2-7 double hexamers around DNA during DNA replication origin licensing.

Authors:  Dirk Remus; Fabienne Beuron; Gökhan Tolun; Jack D Griffith; Edward P Morris; John F X Diffley
Journal:  Cell       Date:  2009-11-05       Impact factor: 41.582

4.  The structural basis for MCM2-7 helicase activation by GINS and Cdc45.

Authors:  Alessandro Costa; Ivar Ilves; Nele Tamberg; Tatjana Petojevic; Eva Nogales; Michael R Botchan; James M Berger
Journal:  Nat Struct Mol Biol       Date:  2011-03-06       Impact factor: 15.369

Review 5.  Helicase loading: how to build a MCM2-7 double-hexamer.

Authors:  Alberto Riera; Silvia Tognetti; Christian Speck
Journal:  Semin Cell Dev Biol       Date:  2014-03-14       Impact factor: 7.727

6.  Cryo-EM structure of a helicase loading intermediate containing ORC-Cdc6-Cdt1-MCM2-7 bound to DNA.

Authors:  Jingchuan Sun; Cecile Evrin; Stefan A Samel; Alejandra Fernández-Cid; Alberto Riera; Hironori Kawakami; Bruce Stillman; Christian Speck; Huilin Li
Journal:  Nat Struct Mol Biol       Date:  2013-07-14       Impact factor: 15.369

7.  A unique DNA entry gate serves for regulated loading of the eukaryotic replicative helicase MCM2-7 onto DNA.

Authors:  Stefan A Samel; Alejandra Fernández-Cid; Jingchuan Sun; Alberto Riera; Silvia Tognetti; M Carmen Herrera; Huilin Li; Christian Speck
Journal:  Genes Dev       Date:  2014-08-01       Impact factor: 11.361
  7 in total
  4 in total

1.  Juvenile Hormone Activates the Transcription of Cell-division-cycle 6 (Cdc6) for Polyploidy-dependent Insect Vitellogenesis and Oogenesis.

Authors:  Zhongxia Wu; Wei Guo; Yingtian Xie; Shutang Zhou
Journal:  J Biol Chem       Date:  2016-01-04       Impact factor: 5.157

2.  Cyclin-dependent kinase inhibitor flavopiridol promotes remyelination in a cuprizone induced demyelination model.

Authors:  Guiyun Mi; Yunyun Gao; Shuai Liu; Enmao Ye; Yanyan Li; Xiao Jin; Hongju Yang; Zheng Yang
Journal:  Cell Cycle       Date:  2016-08-11       Impact factor: 4.534

Review 3.  A structural view of the initiators for chromosome replication.

Authors:  Kin Fan On; Matt Jaremko; Bruce Stillman; Leemor Joshua-Tor
Journal:  Curr Opin Struct Biol       Date:  2018-09-12       Impact factor: 6.809

Review 4.  Myc and the Replicative CMG Helicase: The Creation and Destruction of Cancer: Myc Over-Activation of CMG Helicases Drives Tumorigenesis and Creates a Vulnerability in CMGs for Therapeutic Intervention.

Authors:  Damon R Reed; Mark G Alexandrow
Journal:  Bioessays       Date:  2020-02-20       Impact factor: 4.345
  4 in total

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