Literature DB >> 25483051

DNMT1-associated DNA methylation changes in cancer.

Pavel Bashtrykov1, Albert Jeltsch.   

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Year:  2015        PMID： 25483051      PMCID： PMC4353171          DOI： 10.4161/15384101.2014.989963

Source DB:  PubMed          Journal:  Cell Cycle        ISSN： 1551-4005            Impact factor:   4.534


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  7 in total

Review 1.  A decade of exploring the cancer epigenome - biological and translational implications.

Authors:  Stephen B Baylin; Peter A Jones
Journal:  Nat Rev Cancer       Date:  2011-09-23       Impact factor: 60.716

2.  The DNA methyltransferase Dnmt1 directly interacts with the SET and RING finger-associated (SRA) domain of the multifunctional protein Uhrf1 to facilitate accession of the catalytic center to hemi-methylated DNA.

Authors:  Ahmet Can Berkyurek; Isao Suetake; Kyohei Arita; Kohei Takeshita; Atsushi Nakagawa; Masahiro Shirakawa; Shoji Tajima
Journal:  J Biol Chem       Date:  2013-11-19       Impact factor: 5.157

Review 3.  New concepts in DNA methylation.

Authors:  Albert Jeltsch; Renata Z Jurkowska
Journal:  Trends Biochem Sci       Date:  2014-06-16       Impact factor: 13.807

4.  The replication focus targeting sequence (RFTS) domain is a DNA-competitive inhibitor of Dnmt1.

Authors:  Farisa Syeda; Rebecca L Fagan; Matthew Wean; George V Avvakumov; John R Walker; Sheng Xue; Sirano Dhe-Paganon; Charles Brenner
Journal:  J Biol Chem       Date:  2011-03-09       Impact factor: 5.157

5.  RFTS-deleted DNMT1 enhances tumorigenicity with focal hypermethylation and global hypomethylation.

Authors:  Bo-Kuan Wu; Szu-Chieh Mei; Charles Brenner
Journal:  Cell Cycle       Date:  2014       Impact factor: 4.534

6.  The UHRF1 protein stimulates the activity and specificity of the maintenance DNA methyltransferase DNMT1 by an allosteric mechanism.

Authors:  Pavel Bashtrykov; Gytis Jankevicius; Renata Z Jurkowska; Sergey Ragozin; Albert Jeltsch
Journal:  J Biol Chem       Date:  2013-12-24       Impact factor: 5.157

7.  Targeted mutagenesis results in an activation of DNA methyltransferase 1 and confirms an autoinhibitory role of its RFTS domain.

Authors:  Pavel Bashtrykov; Arumugam Rajavelu; Benjamin Hackner; Sergey Ragozin; Thomas Carell; Albert Jeltsch
Journal:  Chembiochem       Date:  2014-02-13       Impact factor: 3.164
  7 in total
  5 in total

1.  Microrna-217 modulates human skin fibroblast senescence by directly targeting DNA methyltransferase 1.

Authors:  Ben Wang; Rui Du; Xiao Xiao; Zhi-Li Deng; Dan Jian; Hong-Fu Xie; Ji Li
Journal:  Oncotarget       Date:  2017-05-16

2.  Identification of DBCCR1 as a suppressor in the development of lung cancer that is associated with increased DNA methyltransferase 1.

Authors:  Guoren Zhou; Jinjun Ye; Ying Fang; Zhi Zhang; Jingyuan Zhang; Lei Sun; Jifeng Feng
Journal:  Oncotarget       Date:  2017-05-16

3.  A Novel Combination of Withaferin A and Sulforaphane Inhibits Epigenetic Machinery, Cellular Viability and Induces Apoptosis of Breast Cancer Cells.

Authors:  Kendra J Royston; Neha Udayakumar; Kayla Lewis; Trygve O Tollefsbol
Journal:  Int J Mol Sci       Date:  2017-05-19       Impact factor: 5.923

4.  DNMT1 mediates chemosensitivity by reducing methylation of miRNA-20a promoter in glioma cells.

Authors:  Daoyang Zhou; Yingfeng Wan; Dajiang Xie; Yirong Wang; Junhua Wei; Qingfeng Yan; Peng Lu; Lianjie Mo; Jixi Xie; Shuxu Yang; Xuchen Qi
Journal:  Exp Mol Med       Date:  2015-09-04       Impact factor: 8.718

5.  Silencing DNA methyltransferase 1 (DNMT1) inhibits proliferation, metastasis and invasion in ESCC by suppressing methylation of RASSF1A and DAPK.

Authors:  Jian Bai; Xue Zhang; Kai Hu; Bangqing Liu; Haiyong Wang; Angui Li; Feng Lin; Lifei Zhang; Xiaolin Sun; Zhenzong Du; Jianfei Song
Journal:  Oncotarget       Date:  2016-07-12
  5 in total

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