Shih-Han Hung1,2, Herng-Ching Lin3, Chin-Hui Su2,4, Shiu-Dong Chung3,5,6. 1. Department of Otolaryngology, Taipei Medical University Hospital, Taipei, Taiwan. 2. Department of Otolaryngology, School of Medicine, Taipei Medical University, Taipei, Taiwan. 3. Sleep Research Center, Taipei Medical University, Taipei, Taiwan. 4. Department of Otorhinolaryngology, Mackay Memorial Hospital, Taipei, Taiwan. 5. Division of Urology, Department of Surgery, Far Eastern Memorial Hospital, New Taipei City, Taiwan. 6. School of Medicine, Fu-Jen Catholic University, New Taipei City, Taiwan.
Abstract
BACKGROUND: The purpose of this study was to evaluate the association between cholelithiasis and developing sialolithiasis using a population-based coverage database. METHODS: The data for this study were sourced from the Taiwan Longitudinal Health Insurance Database. We included 745 subjects with sialolithiasis as cases and 3725 sex-matched and age-matched subjects without sialolithiasis as controls. RESULTS: Chi-square test revealed a significant difference in the prevalence of prior cholelithiasis between the cases and controls (8.6% vs 4.1%; p < .001). Furthermore, conditional logistic regression analysis indicated that the odds ratio (OR) of prior cholelithiasis for the cases was 2.19 (95% confidence interval [CI] = 1.62-2.98) when compared with the controls after adjusting for monthly income, geographic location, urbanization level, and tobacco use disorder. The adjusted OR of prior cholelithiasis for cases was 2.20 (95% CI = 1.46-3.33) and 2.15 (95% CI = 1.38-3.42) than controls for men and women, respectively. CONCLUSION: This study demonstrates an association between sialolithiasis and cholelithiasis.
BACKGROUND: The purpose of this study was to evaluate the association between cholelithiasis and developing sialolithiasis using a population-based coverage database. METHODS: The data for this study were sourced from the Taiwan Longitudinal Health Insurance Database. We included 745 subjects with sialolithiasis as cases and 3725 sex-matched and age-matched subjects without sialolithiasis as controls. RESULTS: Chi-square test revealed a significant difference in the prevalence of prior cholelithiasis between the cases and controls (8.6% vs 4.1%; p < .001). Furthermore, conditional logistic regression analysis indicated that the odds ratio (OR) of prior cholelithiasis for the cases was 2.19 (95% confidence interval [CI] = 1.62-2.98) when compared with the controls after adjusting for monthly income, geographic location, urbanization level, and tobacco use disorder. The adjusted OR of prior cholelithiasis for cases was 2.20 (95% CI = 1.46-3.33) and 2.15 (95% CI = 1.38-3.42) than controls for men and women, respectively. CONCLUSION: This study demonstrates an association between sialolithiasis and cholelithiasis.
Authors: Kari Hemminki; Otto Hemminki; Anni I M Koskinen; Asta Försti; Kristina Sundquist; Jan Sundquist; Xinjun Li Journal: BMC Nephrol Date: 2018-07-03 Impact factor: 2.388