Literature DB >> 2547964

Molecular characterization and comparison of simian immunodeficiency virus isolates from macaques, mangabeys, and African green monkeys.

R E Benveniste1, D Raben, R W Hill, W B Knott, J E Drummond, L O Arthur, P B Jahrling, W R Morton, L E Henderson, G Heidecker.   

Abstract

Simian immunodeficiency virus (SIV)/Mne has been inoculated into three species of macaques and into baboons. Virus was isolated from all the macaques who subsequently died at 15 to 120 weeks (mean 80 weeks) with various manifestations of immune deficiency. Individual animals varied in their viral antibody profile as a function of time after infection. Independent SIV isolates obtained from African green monkeys and magabeys were compared to SIV/Mne for their ability to replicate in lymphocytes and macrophages and with respect to the immunological relatedness of their viral proteins. Antibodies present in human immunodeficiency virus-2 (HIV-2)-infected individuals were readily detected by the virus produced by a single-cell clone of SIV/Mne.

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Year:  1989        PMID： 2547964

Source DB:  PubMed          Journal:  J Med Primatol        ISSN： 0047-2565            Impact factor:   0.667


  8 in total

1.  Role of immune responses against the envelope and the core antigens of simian immunodeficiency virus SIVmne in protection against homologous cloned and uncloned virus challenge in Macaques.

Authors:  P S Polacino; V Stallard; J E Klaniecki; S Pennathur; D C Montefiori; A J Langlois; B A Richardson; W R Morton; R E Benveniste; S L Hu
Journal:  J Virol       Date:  1999-10       Impact factor: 5.103

2.  Protection of Macaca nemestrina from disease following pathogenic simian immunodeficiency virus (SIV) challenge: utilization of SIV nucleocapsid mutant DNA vaccines with and without an SIV protein boost.

Authors:  R J Gorelick; R E Benveniste; J D Lifson; J L Yovandich; W R Morton; L Kuller; B M Flynn; B A Fisher; J L Rossio; M Piatak; J W Bess; L E Henderson; L O Arthur
Journal:  J Virol       Date:  2000-12       Impact factor: 5.103

3.  Limited breadth of the protective immunity elicited by simian immunodeficiency virus SIVmne gp160 vaccines in a combination immunization regimen.

Authors:  P Polacino; V Stallard; J E Klaniecki; D C Montefiori; A J Langlois; B A Richardson; J Overbaugh; W R Morton; R E Benveniste; S L Hu
Journal:  J Virol       Date:  1999-01       Impact factor: 5.103

4.  Protection of macaques against intrarectal infection by a combination immunization regimen with recombinant simian immunodeficiency virus SIVmne gp160 vaccines.

Authors:  P Polacino; V Stallard; D C Montefiori; C R Brown; B A Richardson; W R Morton; R E Benveniste; S L Hu
Journal:  J Virol       Date:  1999-04       Impact factor: 5.103

5.  Protection of macaques against simian AIDS by immunization with a recombinant vaccinia virus expressing the envelope glycoproteins of simian type D retrovirus.

Authors:  S L Hu; J M Zarling; J Chinn; B M Travis; P A Moran; J Sias; L Kuller; W R Morton; G Heidecker; R E Benveniste
Journal:  Proc Natl Acad Sci U S A       Date:  1989-09       Impact factor: 11.205

6.  Quantitation of a lentivirus in its natural host: simian immunodeficiency virus in African green monkeys.

Authors:  S Hartung; K Boller; K Cichutek; S G Norley; R Kurth
Journal:  J Virol       Date:  1992-04       Impact factor: 5.103

7.  Cholesterol depletion of human immunodeficiency virus type 1 and simian immunodeficiency virus with beta-cyclodextrin inactivates and permeabilizes the virions: evidence for virion-associated lipid rafts.

Authors:  David R M Graham; Elena Chertova; Joanne M Hilburn; Larry O Arthur; James E K Hildreth
Journal:  J Virol       Date:  2003-08       Impact factor: 5.103

8.  Protection of macaques with a simian immunodeficiency virus envelope peptide vaccine based on conserved human immunodeficiency virus type 1 sequences.

Authors:  A Shafferman; P B Jahrling; R E Benveniste; M G Lewis; T J Phipps; F Eden-McCutchan; J Sadoff; G A Eddy; D S Burke
Journal:  Proc Natl Acad Sci U S A       Date:  1991-08-15       Impact factor: 11.205
  8 in total

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