| Literature DB >> 25478946 |
Soham Mandal1, Alexander Hepp, Jens Müller.
Abstract
The DNA lesion 1,N(6)-ethenoadenine (εA) has been investigated with respect to its metal-binding properties. A synthetic DNA duplex comprising an εA : εA mispair readily forms doubly silver(I)-mediated base pairs εA-Ag(I)2-εA, representing the first example for a dinuclear metal-mediated homo base pair of a purine derivative. It also constitutes the first example for a Hoogsteen-type metal-mediated homo base pair within a B-DNA duplex.Entities:
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Year: 2015 PMID: 25478946 DOI: 10.1039/c4dt02663b
Source DB: PubMed Journal: Dalton Trans ISSN: 1477-9226 Impact factor: 4.390