Literature DB >> 25478873

Time to overcome the high, long, and bumpy free energy barrier in a multi-stage process: the generalized steady-state approach.

Alexei V Finkelstein1.   

Abstract

This paper presents a simple but general analytical estimate of the characteristic time of crossing a long, high, and arbitrary bumpy free energy barrier in the course of a sequential (one-dimensional) chemical, biochemical, or physical reaction. This estimate is based on a generalized steady-state approach developed in this paper.

Mesh：

Year:  2014        PMID： 25478873     DOI： 10.1021/jp5109703

Source DB:  PubMed          Journal:  J Phys Chem B        ISSN： 1520-5207            Impact factor:   2.991


  4 in total

1.  Strict experimental evidence that apo-chaperonin GroEL does not accelerate protein folding, although it does accelerate one of its steps.

Authors:  Natalia Y Marchenko; Victor V Marchenkov; Gennady V Semisotnov; Alexei V Finkelstein
Journal:  Proc Natl Acad Sci U S A       Date:  2015-11-24       Impact factor: 11.205

2.  Confinement and Stabilization of Fyn SH3 Folding Intermediate Mimetics within the Cavity of the Chaperonin GroEL Demonstrated by Relaxation-Based NMR.

Authors:  David S Libich; Vitali Tugarinov; Rodolfo Ghirlando; G Marius Clore
Journal:  Biochemistry       Date:  2017-02-08       Impact factor: 3.162

3.  Ligand-induced changes of the apparent transition-state position in mechanical protein unfolding.

Authors:  Johannes Stigler; Matthias Rief
Journal:  Biophys J       Date:  2015-07-21       Impact factor: 4.033

4.  How Can Ice Emerge at 0 °C?

Authors:  Alexei V Finkelstein; Sergiy O Garbuzynskiy; Bogdan S Melnik
Journal:  Biomolecules       Date:  2022-07-13
  4 in total

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