Literature DB >> 25478469

Malignant conversion of oral submucous fibrosis in surgically treated case.

Rajendra Arora1, Dwarkadas Adwani2, Milind Naphade3, Bhushan Bhagat4, Abdul Qahar Qureshi4.   

Abstract

Oral submucous fibrosis (OSMF) is an insidious chronic disease affecting any part of the oral cavity and sometimes the pharynx with epithelial atrophy leading to stiffness of the oral mucosa, causing trismus and inability to eat. However a more serious complication of this disease is the risk of the development of oral carcinoma. We reported the histopathologically proven case of OSMF with initial interincisal mouth opening 2mm which was treated surgically with nasolabial flap technique but failed to follow up and could not do active mouth opening exercises. Malignant conversion of OSMF was seen in this case. This is required to assess the progress and evaluate any malignant transformation at the earliest. So, the importance of active co-operation and frequent follow up cannot be overemphasized. The purpose of this study is to emphasize the importance of regular follow up and frequent biopsies to facilitate oral examination and to check any malignant conversion after the surgery.

Entities:  

Keywords:  Follow-up; Malignant transformation; Mouth opening exercise; Nasolabial flap; Oral submucous fibrosis

Year:  2014        PMID: 25478469      PMCID: PMC4253287          DOI: 10.7860/JCDR/2014/9099.5058

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  6 in total

Review 1.  Oral submucous fibrosis: review on aetiology and pathogenesis.

Authors:  W M Tilakaratne; M F Klinikowski; Takashi Saku; T J Peters; Saman Warnakulasuriya
Journal:  Oral Oncol       Date:  2005-11-28       Impact factor: 5.337

2.  Exercise therapy for trismus in head and neck cancer.

Authors:  P U Dijkstra; M W Sterken; R Pater; F K L Spijkervet; J L N Roodenburg
Journal:  Oral Oncol       Date:  2006-09-18       Impact factor: 5.337

3.  Extended nasolabial flaps in the management of oral submucous fibrosis.

Authors:  R M Borle; P V Nimonkar; R Rajan
Journal:  Br J Oral Maxillofac Surg       Date:  2008-11-07       Impact factor: 1.651

Review 4.  Oral submucous fibrosis, a clinically benign but potentially malignant disease: report of 3 cases and review of the literature.

Authors:  Ajit Auluck; Miriam P Rosin; Lewei Zhang; K N Sumanth
Journal:  J Can Dent Assoc       Date:  2008-10       Impact factor: 1.316

5.  Oral submucous fibrosis: study of 1000 cases from central India.

Authors:  V K Hazarey; D M Erlewad; K A Mundhe; S N Ughade
Journal:  J Oral Pathol Med       Date:  2007-01       Impact factor: 4.253

Review 6.  Pathogenesis of oral submucous fibrosis. Relationship to risk factors associated with oral cancer.

Authors:  R Pillai; P Balaram; K S Reddiar
Journal:  Cancer       Date:  1992-04-15       Impact factor: 6.860

  6 in total
  2 in total

1.  Chronic Fibrosis and Its Progression to Cancer.

Authors:  Taro Yasuma; Esteban C Gabazza
Journal:  Int J Mol Sci       Date:  2022-04-01       Impact factor: 5.923

2.  Effect of Lysyl Oxidase G473 A Polymorphism on Lysyl Oxidase and Total Soluble Collagen Expression in Oral Submucous Fibrosis.

Authors:  Sanjit Mukherjee; Atul Katarkar; Richa Dhariwal; Sweta Mohanty; Basudev Mahato; Jay Gopal Ray; Keya Chaudhuri
Journal:  Asian Pac J Cancer Prev       Date:  2021-08-01
  2 in total

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