Literature DB >> 25478400

Umbilical metastasis as primary manifestation of cancer: a small series and review of the literature.

Kyriakos Psarras1, Nikolaos Symeonidis1, Minas Baltatzis1, Athanasios Notopoulos2, Christina Nikolaidou3.   

Abstract

Umbilical metastasis is a rare manifestation of intra-abdominal cancer. It appears either as the first sign of a primary malignancy or as metastatic site of an already diagnosed cancer, representing an ominous prognostic finding. We report three cases of umbilical metastasis as the first sign of an underlying malignancy. Hypotheses about pathophysiology of umbilical metastasis are based on the embryological origin of the umbilicus and its residual communication with systematic, portal and lymphatic circulation.

Entities:  

Keywords:  Ovarian cancer; Rectal cancer; Sister mary Joseph’s nodule; Umbilical metastasis; Urinary bladder cancer

Year:  2014        PMID： 25478400      PMCID： PMC4253218          DOI： 10.7860/JCDR/2014/9690.4997

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN： 0973-709X


  14 in total

Review 1.  Metastatic tumors of the umbilicus: a review 1830-1989.

Authors:  M R Shetty
Journal:  J Surg Oncol       Date:  1990-11       Impact factor: 3.454

2.  Umbilicus as the only site of metastasis in recurrent ovarian cancer.

Authors:  Hsiao-Wen Tsai; Chiou-Chung Yuan; Peng-Hui Wang
Journal:  J Chin Med Assoc       Date:  2006-05       Impact factor: 2.743

3.  Umbilical metastasis diagnosed by fine needle aspiration.

Authors:  Y Edoute; E Malberger; A Kuten
Journal:  J Surg Oncol       Date:  1990-09       Impact factor: 3.454

4.  Sister Mary Joseph's nodule.

Authors:  Sandra Davar; Dominique Hanna
Journal:  J Cutan Med Surg       Date:  2012 May-Jun       Impact factor: 2.092

5.  Skin involvement as the presenting sign of internal carcinoma. A retrospective study of 7316 cancer patients.

Authors:  D P Lookingbill; N Spangler; F M Sexton
Journal:  J Am Acad Dermatol       Date:  1990-01       Impact factor: 11.527

6.  Metastatic umbilical carcinoma: the Sister Joseph's nodule.

Authors:  M L Chaffins; D A Altman; M R Balle; L Lowe; O G Rodman
Journal:  Cutis       Date:  1993-07

7.  Fine-needle aspiration cytology of Sister Mary Joseph's (paraumbilical) nodules.

Authors:  Uma Handa; Sukant Garg; Harsh Mohan
Journal:  Diagn Cytopathol       Date:  2008-05       Impact factor: 1.582

Review 8.  Sister Mary Joseph nodule from metastatic renal cell carcinoma.

Authors:  P Chen; M R Middlebrook; S M Goldman; C M Sandler
Journal:  J Comput Assist Tomogr       Date:  1998 Sep-Oct       Impact factor: 1.826

9.  Umbilical metastases: current viewpoint.

Authors:  Raimondo Gabriele; Marco Conte; Federico Egidi; Mario Borghese
Journal:  World J Surg Oncol       Date:  2005-02-21       Impact factor: 2.754

10.  Sister Mary Joseph's nodule: Three case reports.

Authors:  Andreas Larentzakis; Dimitrios Theodorou; Klio Fili; Anna Manataki; Vasiliki Bizimi; Michael Tibishrani; Stylianos Katsaragakis
Journal:  Cases J       Date:  2008-09-24
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  3 in total

1.  Sister Mary Joseph's nodule: a very useful indicator of significant internal pathology.

Authors:  John D Gilbert; Roger W Byard
Journal:  Forensic Sci Med Pathol       Date:  2015-10-17       Impact factor: 2.007

2.  Wide excision and reconstruction surgery for recurrent sweat gland umbilical adenocarcinoma followed by chemotherapy can prevent the risk of recurrences.

Authors:  Adeodatus Yuda Handaya; Nova Yuli Prasetyo Budi; Guntur Marganing Adi Nugroho; Aditya Rifqi Fauzi
Journal:  BMC Surg       Date:  2018-10-12       Impact factor: 2.102

Review 3.  Cutaneous Metastases in Ovarian Cancer.

Authors:  Isao Otsuka
Journal:  Cancers (Basel)       Date:  2019-09-02       Impact factor: 6.639
  3 in total

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