Literature DB >> 25478386

Neurorickettsioses: a rare presentation with stroke in a young adult.

Praveen Kumar S1, Pramod K2.   

Abstract

Acute stroke-like presentations due to rickettsial infections have been sparsely reported in literature. We report a young patient who presented with high grade fever and acute encephalopathy with right hemiplegia. CT head showed left cerebral, bilateral thalamic and midbrain infarcts. The stroke in young work-up for conventional and non-conventional risk factors including few infections known to cause cerebral vasculitis was negative. He did not respond to empirical antimalarials and antibiotics. With a high index of suspicion of his 'febrile cerebrovasculitis' like presentation, serological test for rickettsia was done and found to be positive. He responded to doxycycline. This case expands the spectrum of presentation of neurorickettsioses and highlights the importance of considering rickettsial vasculitis as one of the potentially treatable causes of infections causing stroke.

Entities:  

Keywords:  Endothelial dysfunction; Febrile cerebrovasculitis; Neurorickettsioses; Rickettsia; Stroke-in-young

Year:  2014        PMID: 25478386      PMCID: PMC4253204          DOI: 10.7860/JCDR/2014/9646.4996

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  4 in total

1.  Acute febrile cerebrovasculitis: a syndrome of unknown, perhaps rickettsial, cause.

Authors:  R P Wenzel; F G Hayden; D H Gröschel; R A Salata; W S Young; J E Greenlee; S Newman; P J Miller; K E Hechemy; W Burgdorfer
Journal:  Ann Intern Med       Date:  1986-05       Impact factor: 25.391

Review 2.  Rickettsiae and rickettsial infections: the current state of knowledge.

Authors:  David H Walker
Journal:  Clin Infect Dis       Date:  2007-07-15       Impact factor: 9.079

3.  Acute febrile cerebrovasculitis. A non-spotted fever group rickettsial disease.

Authors:  C C Linnemann; C I Pretzman; E D Peterson
Journal:  Arch Intern Med       Date:  1989-07

Review 4.  The interface between stroke and infectious disease: infectious diseases leading to stroke and infections complicating stroke.

Authors:  Georgios Manousakis; Matthew B Jensen; Marcus R Chacon; Justin A Sattin; Ross L Levine
Journal:  Curr Neurol Neurosci Rep       Date:  2009-01       Impact factor: 6.030

  4 in total

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