Sharabeh Hezarkhani1, Sima Sedighi2, Mehrdad Aghaei2, Maryam Shamekhi3, Mahin Nomali4. 1. Endocrinologist, Assistant Professor, Department of Internal Medicine, Faculty of Medicine, Golestan University of Medical Sciences , Gorgan, Iran . 2. Rheumatologist, Assistant Professor, Joints, Bone and Connective Tissue Research Centre (JBCRC), Golestan University of Medical Sciences , Gorgan, Iran . 3. Medical Doctor (MD), Golestan University of Medical Sciences , Gorgan, Iran . 4. Nurse (BSN), Golestan University of Medical Sciences , Gorgan, Iran .
Abstract
BACKGROUND: Autoimmune thyroid diseases (ATDs) are the most common endocrine diseases which result in rheumatologic manifestations. Some studies have shown association between rheumatologic disorders and ATDs. Thus, the aim of this study was to assess the frequency of rheumatologic manifestations in patients with ATDs. MATERIALS AND METHODS: In this cross-sectional descriptive study during 2010 to 2011, 65 patients with ATDs referred to the Rheumatology clinic of 5 Azar Hospital in Gorgan (North of Iran) were studied via systematic random sampling and patients with positive antithyroid peroxides (anti-TPO) were included in the study. These patients were examined by a rheumatologist for diagnosis of rheumatologic manifestations and tested for serum levels of TSH, Free T3 and T4, Anti-Nuclear Antibodies (ANAs) and Rheumatoid Factor (RF). SPSS software (version 16) and descriptive statistics were used for data analysis. RESULTS: Nine males (14.8%) and 56 females (86.2%) with mean age of 38.81±1.44 years were studied. Overall, Rheumatologic manifestations were seen in 86.2 % (n=56). In this study, the most frequent rheumatologic manifestations were Carpal Tunnel Syndrome (36.1%) and Osteoarthritis (23%). Reynaud's phenomenon (RP) (10.7%), Discopathy (8.9%), Fibromyalgia (5.3%), Myopathy (3.6%), Rheumatoid arthritis (3.6%) and trigger finger (3.6%) were other manifestations, respectively. CONCLUSION: In this region, there is a high frequency of rheumatologic manifestations in patients with ATDs. Thus, initial evaluation and regular checkings are recommended.
BACKGROUND:Autoimmune thyroid diseases (ATDs) are the most common endocrine diseases which result in rheumatologic manifestations. Some studies have shown association between rheumatologic disorders and ATDs. Thus, the aim of this study was to assess the frequency of rheumatologic manifestations in patients with ATDs. MATERIALS AND METHODS: In this cross-sectional descriptive study during 2010 to 2011, 65 patients with ATDs referred to the Rheumatology clinic of 5 Azar Hospital in Gorgan (North of Iran) were studied via systematic random sampling and patients with positive antithyroid peroxides (anti-TPO) were included in the study. These patients were examined by a rheumatologist for diagnosis of rheumatologic manifestations and tested for serum levels of TSH, Free T3 and T4, Anti-Nuclear Antibodies (ANAs) and Rheumatoid Factor (RF). SPSS software (version 16) and descriptive statistics were used for data analysis. RESULTS: Nine males (14.8%) and 56 females (86.2%) with mean age of 38.81±1.44 years were studied. Overall, Rheumatologic manifestations were seen in 86.2 % (n=56). In this study, the most frequent rheumatologic manifestations were Carpal Tunnel Syndrome (36.1%) and Osteoarthritis (23%). Reynaud's phenomenon (RP) (10.7%), Discopathy (8.9%), Fibromyalgia (5.3%), Myopathy (3.6%), Rheumatoid arthritis (3.6%) and trigger finger (3.6%) were other manifestations, respectively. CONCLUSION: In this region, there is a high frequency of rheumatologic manifestations in patients with ATDs. Thus, initial evaluation and regular checkings are recommended.
Authors: Ivica Lazúrová; Karim Benhatchi; Jozef Rovenský; Darina Kozáková; Hedviga Wagnerová; Mária Tajtáková; Yehuda Shoenfeld; Z Macejova Journal: Ann N Y Acad Sci Date: 2009-09 Impact factor: 5.691
Authors: Kristien Boelaert; Paul R Newby; Matthew J Simmonds; Roger L Holder; Jacqueline D Carr-Smith; Joanne M Heward; Nilusha Manji; Amit Allahabadia; Mary Armitage; Krishna V Chatterjee; John H Lazarus; Simon H Pearce; Bijay Vaidya; Stephen C Gough; Jayne A Franklyn Journal: Am J Med Date: 2010-02 Impact factor: 4.965