Literature DB >> 25478361

Carcinosarcoma masquerading as giant cystic hematomasurekha.

Surekha B Hippargi1, Anita P Javalgi2, Anirudh V Kushtagi2, Padmaja R Kulkarni2, Mamta K2.   

Abstract

Carcinoarcoma of breast is rare tumor with aggressive behaviour and poor prognosis. Histologically it is biphasic tumor with epithelial and mesenchymal component. Very few cases of carcinosarcoma, its presentation and behaviour have been reported in the literature, and due to its bizarre behaviour it is a diagnostic challenge to pathologist and clinicians. Here we present a rare case of carcinosarcoma breast in a 55-year-old female who initially presented with cystic mass( lump) in right breast which was reported as organised hematoma on FNAC, on frozen section it was diagnosed as malignant cystic tumour. This was followed by mastectomy. Histopathology with immune markers, the case was diagnosed as metaplastic carcinoma with biphasic type called carcinosarcoma. The case merits presentation because of its rare presentation as cystic lesion and difficult to diagnose mainly due to sarcomatous elements. An accurate diagnosis of this aggressive tumour is essential in order to optimally tailor adjuvant therapy.

Entities:  

Keywords:  Breast cancer; Carcinosarcoma; Cystic mass; Organised hematoma

Year:  2014        PMID: 25478361      PMCID: PMC4253179          DOI: 10.7860/JCDR/2014/9123.5066

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  6 in total

1.  Carcinosarcoma of the breast.

Authors:  Muhammad Ameen Abbasi; Humera Mahmood; Muhammad Faheem; Khurshid Ahmed Khan; Javed Irfan
Journal:  J Coll Physicians Surg Pak       Date:  2012-05       Impact factor: 0.711

2.  Sarcomatoid neoplasms of the breast: proposed definitions for biphasic and monophasic sarcomatoid mammary carcinomas.

Authors:  M P Foschini; R E Dina; V Eusebi
Journal:  Semin Diagn Pathol       Date:  1993-05       Impact factor: 3.464

3.  Metaplastic carcinoma of the breast (carcinosarcoma variant): a case report.

Authors:  Anjali Patrikar; Sabiha Maimoon; Sadhana Mahore; M A Akhtar; Anne Wilkinson
Journal:  Indian J Pathol Microbiol       Date:  2007-04       Impact factor: 0.740

4.  Biologic distinctions and therapeutic implications of sarcomatoid metaplasia of epithelial carcinoma of the breast.

Authors:  H Gutman; R E Pollock; N A Janjan; D A Johnston
Journal:  J Am Coll Surg       Date:  1995-02       Impact factor: 6.113

5.  Biphasic metaplastic sarcomatoid carcinoma of the breast.

Authors:  B T Hennessy; S Giordano; K Broglio; Z Duan; J Trent; T A Buchholz; G Babiera; G N Hortobagyi; V Valero
Journal:  Ann Oncol       Date:  2006-02-09       Impact factor: 32.976

6.  Carcinosarcoma of the breast: two case reports and review of the literature.

Authors:  Kristi M Esses; Ramona M Hagmaier; Susan A Blanchard; John J Lazarchick; Adam I Riker
Journal:  Cases J       Date:  2009-01-06
  6 in total

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