Sonali Bhattar1, Preena Bhalla2, Deepti Rawat3, Reva Tripathi4, Ravinder Kaur2, Kabir Sardana5. 1. Senior Resident, Department of Microbiology, Maulana Azad Medical College , Delhi University, New Delhi, India . 2. Director Professor, Department of Microbiology, Maulana Azad Medical College , Delhi University, New Delhi, India . 3. Assistant Professor, Department of Microbiology, Maulana Azad Medical College , Delhi University, New Delhi, India . 4. Director Professor and HOD, Department of Obstetrics & Gynaecology, Maulana Azad Medical College , Delhi University, New Delhi, India . 5. Associate Professor, Department of Dermatology & STDs, Maulana Azad Medical College , Delhi University, New Delhi, India .
Abstract
BACKGROUND: Sexually transmitted infections (STIs) plays a major role in the spread of Human immunodeficiency virus (HIV) due to common route of transmission. These infections display an epidemiological synergy with HIV. AIM: The aim of this study was to analyse the correlation of CD4 T lymphocyte cell count, HIV-1 plasma viral load with Reproductive tract infections/Sexually transmitted infections (RTIs/STIs) in HIV infected females. MATERIALS AND METHODS: The study included 60 HIV infected females. An informed consent was taken from all the study subjects. Relevant specimens (genital specimen and blood) were collected for laboratory diagnosis of various RTIs/STIs, CD4 cell count and plasma viral load estimation. RESULTS: Mean CD4 count of females with bacterial vaginosis, vaginal candidiasis, trichomoniasis, syphilis and herpes simplex infection were lower as compared to other HIV infected cases and mean plasma viral load of bacterial vaginosis, vaginal candidiasis, trichomoniasis and syphilis were higher as compared to other HIV infected cases but this difference was not statistically significant. CONCLUSION: This study highlights the importance of routine screening for STIs/RTIs of all the HIV infected females for RTIs/STIs irrespective of CD4 cell count and plasma viral load.
BACKGROUND: Sexually transmitted infections (STIs) plays a major role in the spread of Human immunodeficiency virus (HIV) due to common route of transmission. These infections display an epidemiological synergy with HIV. AIM: The aim of this study was to analyse the correlation of CD4 T lymphocyte cell count, HIV-1 plasma viral load with Reproductive tract infections/Sexually transmitted infections (RTIs/STIs) in HIV infected females. MATERIALS AND METHODS: The study included 60 HIV infected females. An informed consent was taken from all the study subjects. Relevant specimens (genital specimen and blood) were collected for laboratory diagnosis of various RTIs/STIs, CD4 cell count and plasma viral load estimation. RESULTS: Mean CD4 count of females with bacterial vaginosis, vaginal candidiasis, trichomoniasis, syphilis and herpes simplex infection were lower as compared to other HIV infected cases and mean plasma viral load of bacterial vaginosis, vaginal candidiasis, trichomoniasis and syphilis were higher as compared to other HIV infected cases but this difference was not statistically significant. CONCLUSION: This study highlights the importance of routine screening for STIs/RTIs of all the HIV infected females for RTIs/STIs irrespective of CD4 cell count and plasma viral load.
Authors: J N Nkengasong; L Kestens; P D Ghys; S Koblavi-Dème; C Bilé; M Kalou; L K Ya; V Traoré-Ettiègne; C Maurice; M Laga; S Z Wiktor; A E Greenberg Journal: J Infect Dis Date: 2001-03-16 Impact factor: 5.226
Authors: G U Natividad-Villanueva; E Santiago; R M Manalastas; H W Brown; J Ingersoll; A M Caliendo; K H Mayer; S Cu-Uvin Journal: Int J STD AIDS Date: 2003-12 Impact factor: 1.359