Literature DB >> 25477231

Mediating effects on health-related quality of life in adults with osteoporosis: a structural equation modeling.

C-Y Huang1, L-C Liao, K-M Tong, H-L Lai, W-K Chen, C-I Chen, C-Y Lu, F-J Chen.   

Abstract

UNLABELLED: Participants with physical limitation and high degree of pain had poor mental and physical health-related quality of life. In addition, the more support and exercise that the participants had, the more likely they were to report better health-related quality of life.
INTRODUCTION: Osteoporosis is a public health threat worldwide. The aim of this study is to examine the effects of individual demographics, disease characteristics, and social support on health-related quality of life (HrQoL) of adults with osteoporosis. Most psychosocial studies focused on the relationships but not the specific construct of social support on HrQoL.
METHODS: In a correlational design, face-to-face, structured interviews were employed to collect information. Study questionnaires included a demographic sheet, the modified Social Support Inventory, and the Short-Form 36 scales on a convenience sample of 161 individuals recruited from four outpatient centers. Using the structural equation modeling approach, all relationships among factors, mediators, and HrQoL were analyzed.
RESULTS: The mean duration of osteoporosis was longer than 5 years. Participants who exercised more than three times per week had greater HrQoL than individuals who exercised less frequently. Participants with physical limitation and high degree of pain had poor mental and physical HrQoL. The more support that the participants perceived, the more likely they were to report better HrQoL. The best fitted structural equation modeling (SEM) model included individual demographics and physical function, and social support as significant predictors on HrQoL, with informational support and physical function acting as mediators in those relationships. Moreover, this structural model explained 35, 42, and 40 % of the variance on activity of daily living (ADL), physical, and mental health-related quality of life.
CONCLUSIONS: The more informational support that individuals have, the more likely they were to report better HrQoL. Individuals with osteoporosis who have lower pain and more exercise are considered having better HrQoL. Further longitudinal research will help clarify the direction of these relationships.

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Year:  2014        PMID: 25477231     DOI: 10.1007/s00198-014-2963-3

Source DB:  PubMed          Journal:  Osteoporos Int        ISSN: 0937-941X            Impact factor:   4.507


  23 in total

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Review 2.  Health-related quality of life in patients with osteoporosis in the absence of vertebral fracture: a systematic review.

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8.  Unraveling estrogen action in osteoporosis.

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Review 9.  Depression and low bone mineral density: a meta-analysis of epidemiologic studies.

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10.  Fear of falling, fracture history, and comorbidities are associated with health-related quality of life among European and US women with osteoporosis in a large international study.

Authors:  F Guillemin; L Martinez; M Calvert; C Cooper; T Ganiats; M Gitlin; R Horne; A Marciniak; J Pfeilschifter; S Shepherd; A Tosteson; S Wade; D Macarios; N Freemantle
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3.  Quality of Life Is Related to Social Support in Elderly Osteoporosis Patients in a Chinese Population.

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4.  Social support as a mediator between sleep disturbances, depressive symptoms, and health-related quality of life in patients undergoing hemodialysis.

Authors:  Kuei-Ching Pan; Shih-Yuan Hung; Chun-I Chen; Chu-Yun Lu; Mei-Ling Shih; Chiung-Yu Huang
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5.  Prevalent osteoporotic fractures in 622 obese and non- obese menopausal women.

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