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Literature DB >> 25475181

Past experience resets behavior: CaMK takes the heat.

Swathi Yadlapalli¹, Khursheed A Wani¹, X Z Shawn Xu².

Abstract

How past experiences reshape behavior is not well understood. In this issue, two studies (Schild et al., 2014; Yu et al., 2014) dissected the molecular mechanisms underlying experience-dependent plasticity in thermosensory behavior. They show that Ca(2+)/calmodulin-dependent kinase I (CaMKI) regulates thermal preferences according to past experience.

Entities: Chemical Disease Gene Species

Year: 2014 PMID： 25475181 PMCID： PMC4301849 DOI： 10.1016/j.neuron.2014.11.014

Source DB: PubMed Journal: Neuron ISSN： 0896-6273 Impact factor: 17.173

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References

16 in total

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Past experience resets behavior: CaMK takes the heat.

1. The C. elegans thermosensory neuron AFD responds to warming.

2. Normal and mutant thermotaxis in the nematode Caenorhabditis elegans.

Review 3. Running hot and cold: behavioral strategies, neural circuits, and the molecular machinery for thermotaxis in C. elegans and Drosophila.

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