OBJECTIVE: To examine the differences in quality of life for vestibular schwannoma patients undergoing conservative management, gamma knife, and surgery. PATIENTS: Vestibular schwannoma patients without a diagnosis of NF2. INTERVENTIONS: Vestibular schwannoma treatment or conservative management. MAIN OUTCOME MEASURES: Penn Acoustic Neuroma Quality of Life (PANQOL) survey scores (0-100). RESULTS: One hundred eighty-six patients (98 conservative, 49 gamma knife, 39 surgery) were included. Mean patient age (years) of the surgery group (49 ± 14) was significantly younger than both the conservative (58 ± 13) and gamma knife group (59 ± 12) (p < 0.001). Mean follow-up time was 2.6 years.Tumor size (mm) was found to be significantly different between the conservative (8 ± 4.8), gamma knife (18 ± 5.9), and surgery (22 ± 8.3) groups (p < 0.001). Speech recognition threshold and speech discrimination percentage were significantly better for the conservative group compared to the gamma knife or surgery groups (p < 0.001).The hearing domain scores seemed better for the conservative group (62 ± 26) when compared to the surgery group (47 ± 25). The general and total domain scores were similar for all treatment groups, whereas the quality-of-life scores for gamma knife and surgery were similar. CONCLUSION: Although surgery groups' significantly larger tumors and worse hearing were apparent in specific PANQOL domains, all patients achieved a similar general level of quality of life.
OBJECTIVE: To examine the differences in quality of life for vestibular schwannomapatients undergoing conservative management, gamma knife, and surgery. PATIENTS: Vestibular schwannomapatients without a diagnosis of NF2. INTERVENTIONS:Vestibular schwannoma treatment or conservative management. MAIN OUTCOME MEASURES: Penn Acoustic Neuroma Quality of Life (PANQOL) survey scores (0-100). RESULTS: One hundred eighty-six patients (98 conservative, 49 gamma knife, 39 surgery) were included. Mean patient age (years) of the surgery group (49 ± 14) was significantly younger than both the conservative (58 ± 13) and gamma knife group (59 ± 12) (p < 0.001). Mean follow-up time was 2.6 years.Tumor size (mm) was found to be significantly different between the conservative (8 ± 4.8), gamma knife (18 ± 5.9), and surgery (22 ± 8.3) groups (p < 0.001). Speech recognition threshold and speech discrimination percentage were significantly better for the conservative group compared to the gamma knife or surgery groups (p < 0.001).The hearing domain scores seemed better for the conservative group (62 ± 26) when compared to the surgery group (47 ± 25). The general and total domain scores were similar for all treatment groups, whereas the quality-of-life scores for gamma knife and surgery were similar. CONCLUSION: Although surgery groups' significantly larger tumors and worse hearing were apparent in specific PANQOL domains, all patients achieved a similar general level of quality of life.
Authors: B Delgado-Vargas; M Medina; R Polo; A Lloris; M Vaca; C Pérez; A Cordero; I Cobeta Journal: Acta Otorhinolaryngol Ital Date: 2017-11-30 Impact factor: 2.124
Authors: Wouter L Lodder; Guleed H Adan; Chung S Chean; Tristram H Lesser; Samuel C Leong Journal: Eur Arch Otorhinolaryngol Date: 2017-04-08 Impact factor: 2.503
Authors: Wouter L Lodder; Bernard F A M van der Laan; Tristram H Lesser; Samuel C Leong Journal: Eur Arch Otorhinolaryngol Date: 2018-01-12 Impact factor: 2.503
Authors: Roland Goldbrunner; Michael Weller; Jean Regis; Morten Lund-Johansen; Pantelis Stavrinou; David Reuss; D Gareth Evans; Florence Lefranc; Kita Sallabanda; Andrea Falini; Patrick Axon; Olivier Sterkers; Laura Fariselli; Wolfgang Wick; Joerg-Christian Tonn Journal: Neuro Oncol Date: 2020-01-11 Impact factor: 12.300
Authors: May N Tsao; Arjun Sahgal; Wei Xu; Antonio De Salles; Motohiro Hayashi; Marc Levivier; Lijun Ma; Roberto Martinez; Jean Régis; Sam Ryu; Ben J Slotman; Ian Paddick Journal: J Radiosurg SBRT Date: 2017