Literature DB >> 25473914

IL-18 is not therapeutic for neovascular age-related macular degeneration.

Yoshio Hirano1, Tetsuhiro Yasuma1, Takeshi Mizutani2, Benjamin J Fowler1, Valeria Tarallo3, Reo Yasuma1, Younghee Kim1, Ana Bastos-Carvalho1, Nagaraj Kerur1, Bradley D Gelfand4, Sasha Bogdanovich1, Shikun He5, Xiaohui Zhang6, Miho Nozaki2, Ryo Ijima7, Hiroki Kaneko7, Yuichiro Ogura2, Hiroko Terasaki7, Hiroshi Nagai8, Isao Haro9, Gabriel Núñez10, Balamurali K Ambati11, David R Hinton5, Jayakrishna Ambati12.   

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Year:  2014        PMID: 25473914      PMCID: PMC4275546          DOI: 10.1038/nm.3671

Source DB:  PubMed          Journal:  Nat Med        ISSN: 1078-8956            Impact factor:   53.440


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  29 in total

Review 1.  Animal models of choroidal and retinal neovascularization.

Authors:  Hans E Grossniklaus; Shin J Kang; Lennart Berglin
Journal:  Prog Retin Eye Res       Date:  2010-05-19       Impact factor: 21.198

2.  Daily administration of interleukin-18 causes myocardial dysfunction in healthy mice.

Authors:  Per Reidar Woldbaek; Jørn Bodvar Sande; Taevje Andreas Strømme; Per Kristian Lunde; Srdjan Djurovic; Torstein Lyberg; Geir Christensen; Theis Tønnessen
Journal:  Am J Physiol Heart Circ Physiol       Date:  2005-04-08       Impact factor: 4.733

3.  The effect of daily administration of IL-18 on cardiac structure and function.

Authors:  A Platis; Q Yu; D Moore; Ev Khojeini; P Tsau; Df Larson
Journal:  Perfusion       Date:  2008-07       Impact factor: 1.972

4.  Vascular endothelial growth factor-A is a survival factor for retinal neurons and a critical neuroprotectant during the adaptive response to ischemic injury.

Authors:  Kazuaki Nishijima; Yin-Shan Ng; Lichun Zhong; John Bradley; William Schubert; Nobuo Jo; Jo Akita; Steven J Samuelsson; Gregory S Robinson; Anthony P Adamis; David T Shima
Journal:  Am J Pathol       Date:  2007-07       Impact factor: 4.307

5.  IL-18 induction of osteopontin mediates cardiac fibrosis and diastolic dysfunction in mice.

Authors:  Qianli Yu; Randy Vazquez; Elham Vali Khojeini; Chirag Patel; Raj Venkataramani; Douglas F Larson
Journal:  Am J Physiol Heart Circ Physiol       Date:  2009-05-08       Impact factor: 4.733

6.  Sequence- and target-independent angiogenesis suppression by siRNA via TLR3.

Authors:  Mark E Kleinman; Kiyoshi Yamada; Atsunobu Takeda; Vasu Chandrasekaran; Miho Nozaki; Judit Z Baffi; Romulo J C Albuquerque; Satoshi Yamasaki; Masahiro Itaya; Yuzhen Pan; Binoy Appukuttan; Daniel Gibbs; Zhenglin Yang; Katalin Karikó; Balamurali K Ambati; Traci A Wilgus; Luisa A DiPietro; Eiji Sakurai; Kang Zhang; Justine R Smith; Ethan W Taylor; Jayakrishna Ambati
Journal:  Nature       Date:  2008-03-26       Impact factor: 49.962

Review 7.  The dual effects of interleukin-18 in tumor progression.

Authors:  Sunyoung Park; Soyoung Cheon; Daeho Cho
Journal:  Cell Mol Immunol       Date:  2007-10       Impact factor: 11.530

8.  Interleukin-1β inhibition prevents choroidal neovascularization and does not exacerbate photoreceptor degeneration.

Authors:  Sophie Lavalette; William Raoul; Marianne Houssier; Serge Camelo; Olivier Levy; Bertrand Calippe; Laurent Jonet; Francine Behar-Cohen; Sylvain Chemtob; Xavier Guillonneau; Christophe Combadière; Florian Sennlaub
Journal:  Am J Pathol       Date:  2011-05       Impact factor: 4.307

9.  DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration.

Authors:  Hiroki Kaneko; Sami Dridi; Valeria Tarallo; Bradley D Gelfand; Benjamin J Fowler; Won Gil Cho; Mark E Kleinman; Steven L Ponicsan; William W Hauswirth; Vince A Chiodo; Katalin Karikó; Jae Wook Yoo; Dong-ki Lee; Majda Hadziahmetovic; Ying Song; Smita Misra; Gautam Chaudhuri; Frank W Buaas; Robert E Braun; David R Hinton; Qing Zhang; Hans E Grossniklaus; Jan M Provis; Michele C Madigan; Ann H Milam; Nikki L Justice; Romulo J C Albuquerque; Alexander D Blandford; Sasha Bogdanovich; Yoshio Hirano; Jassir Witta; Elaine Fuchs; Dan R Littman; Balamurali K Ambati; Charles M Rudin; Mark M W Chong; Patrick Provost; Jennifer F Kugel; James A Goodrich; Joshua L Dunaief; Judit Z Baffi; Jayakrishna Ambati
Journal:  Nature       Date:  2011-02-06       Impact factor: 49.962

10.  CCR3 is a target for age-related macular degeneration diagnosis and therapy.

Authors:  Atsunobu Takeda; Judit Z Baffi; Mark E Kleinman; Won Gil Cho; Miho Nozaki; Kiyoshi Yamada; Hiroki Kaneko; Romulo J C Albuquerque; Sami Dridi; Kuniharu Saito; Brian J Raisler; Steven J Budd; Pete Geisen; Ariel Munitz; Balamurali K Ambati; Martha G Green; Tatsuro Ishibashi; John D Wright; Alison A Humbles; Craig J Gerard; Yuichiro Ogura; Yuzhen Pan; Justine R Smith; Salvatore Grisanti; M Elizabeth Hartnett; Marc E Rothenberg; Jayakrishna Ambati
Journal:  Nature       Date:  2009-06-14       Impact factor: 49.962

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  20 in total

1.  Reply to IL-18 is not therapeutic for neovascular age-related macular degeneration.

Authors:  Sarah L Doyle; Peter Adamson; Francisco J López; Peter Humphries; Matthew Campbell
Journal:  Nat Med       Date:  2014-12       Impact factor: 53.440

Review 2.  Inflammatory Mechanisms of Age-related Macular Degeneration.

Authors:  Jared E Knickelbein; Chi-Chao Chan; H Nida Sen; Frederick L Ferris; Robert B Nussenblatt
Journal:  Int Ophthalmol Clin       Date:  2015

Review 3.  Inflammasomes, the eye and anti-inflammasome therapy.

Authors:  P Yerramothu; A K Vijay; M D P Willcox
Journal:  Eye (Lond)       Date:  2017-11-24       Impact factor: 3.775

4.  DICER1/Alu RNA dysmetabolism induces Caspase-8-mediated cell death in age-related macular degeneration.

Authors:  Younghee Kim; Valeria Tarallo; Nagaraj Kerur; Tetsuhiro Yasuma; Bradley D Gelfand; Ana Bastos-Carvalho; Yoshio Hirano; Reo Yasuma; Takeshi Mizutani; Benjamin J Fowler; Shengjian Li; Hiroki Kaneko; Sasha Bogdanovich; Balamurali K Ambati; David R Hinton; William W Hauswirth; Razqallah Hakem; Charles Wright; Jayakrishna Ambati
Journal:  Proc Natl Acad Sci U S A       Date:  2014-10-27       Impact factor: 11.205

Review 5.  Diverse roles of macrophages in intraocular neovascular diseases: a review.

Authors:  Ye-Di Zhou; Shigeo Yoshida; Ying-Qian Peng; Yoshiyuki Kobayashi; Lu-Si Zhang; Luo-Sheng Tang
Journal:  Int J Ophthalmol       Date:  2017-12-18       Impact factor: 1.779

6.  Dry Age-Related Macular Degeneration Pharmacology.

Authors:  Charles B Wright; Jayakrishna Ambati
Journal:  Handb Exp Pharmacol       Date:  2017

7.  Inflammasomes Induced by 7-Ketocholesterol and Other Stimuli in RPE and in Bone Marrow-Derived Cells Differ Markedly in Their Production of IL-1β and IL-18.

Authors:  Guangpu Shi; Siqi Chen; Wambui S Wandu; Osato Ogbeifun; Lindsey F Nugent; Arvydas Maminishkis; Samuel J H Hinshaw; Ignacio R Rodriguez; Igal Gery
Journal:  Invest Ophthalmol Vis Sci       Date:  2015-02-12       Impact factor: 4.799

Review 8.  Role of inflammasome activation in neovascular age-related macular degeneration.

Authors:  Alexander G Marneros
Journal:  FEBS J       Date:  2021-11-12       Impact factor: 5.622

9.  Nucleoside Reverse Transcriptase Inhibitors Suppress Laser-Induced Choroidal Neovascularization in Mice.

Authors:  Takeshi Mizutani; Benjamin J Fowler; Younghee Kim; Reo Yasuma; Laura A Krueger; Bradley D Gelfand; Jayakrishna Ambati
Journal:  Invest Ophthalmol Vis Sci       Date:  2015-11       Impact factor: 4.799

Review 10.  Inflammation and its role in age-related macular degeneration.

Authors:  Anu Kauppinen; Jussi J Paterno; Janusz Blasiak; Antero Salminen; Kai Kaarniranta
Journal:  Cell Mol Life Sci       Date:  2016-02-06       Impact factor: 9.261

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